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BlephEx is a medical device used in the fields of ophthalmology and optometry to treat blepharitis and dry eye disease. [1] The handheld device is used by a doctor to exfoliate the eyelid [2] at the lash line and remove the inflammatory biofilm [3] that leads to chronic lid disease and discomfort.
Lid hygiene measures such as warm compresses and lid scrubs were found to be effective in providing symptomatic relief for participants with anterior and posterior blepharitis. [20] Lotilaner (Xdemvy) was approved for medical use in the United States in July 2023, for the treatment of Demodex blepharitis. [21]
Demodex / ˈ d ɛ m ə d ɛ k s / is a genus of tiny mites that live in or near hair follicles of mammals. Around 65 species of Demodex are known. [ 2 ] Two species live on humans : Demodex folliculorum and Demodex brevis , both frequently referred to as eyelash mites , alternatively face mites or skin mites .
Demodex folliculorum is a microscopic mite that can survive only on the skin of humans. [ 2 ] [ 3 ] Most people have D. folliculorum on their skin. Usually, the mites do not cause any harm, so are considered an example of commensalism rather than parasitism ; [ 4 ] but they can cause disease, known as demodicosis .
Demodicosis / ˌ d ɛ m ə d ə ˈ k oʊ s ɪ s /, also called Demodex folliculitis in humans [1] and demodectic mange (/ d ɛ m ə ˈ d ɛ k t ɪ k /) or red mange in animals, is caused by a sensitivity to and overpopulation of Demodex spp. as the host's immune system is unable to keep the mites under control. Demodex is a genus of mite in the ...
Treatment can include warm compresses to thin the secretions and eyelid scrubs with a commercial eyelid cleanser or baby shampoo, [17] [13] or emptying ("expression") of the gland by a professional. Lifitegrast and ciclosporin are topical medication commonly used to control the inflammation and improve the oil quality.
Demodex brevis is one of the two species of face mite that inhabit humans (the other being Demodex folliculorum). They are about half as long, at 0.15 to 0.2 mm (6 to 8 thousandths of an inch), [1] as D. folliculorum, but otherwise have few differences. Most of the article on Demodex folliculorum applies equally to D. brevis.
Sarcoptes and Demodex species are involved in mange, but both of these genera are also involved in human skin diseases (by convention only, not called mange). Sarcoptes in humans is especially severe symptomatically, and causes the condition scabies noted above. [citation needed]
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