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From the time of Plato through the Middle Ages, the quadrivium (plural: quadrivia [2]) was a grouping of four subjects or arts—arithmetic, geometry, music, and astronomy—that formed a second curricular stage following preparatory work in the trivium, consisting of grammar, logic, and rhetoric.
The rabbit test became a widely used bioassay (animal-based test) to test for pregnancy. The term "rabbit test" was first recorded in 1949, and was the origin of a common euphemism, "the rabbit died", for a positive pregnancy test. [4] The phrase was, in fact, based on a common misconception about the test.
At the end of the second week of development, some cells of the trophoblast penetrate and form rounded columns into the syncytiotrophoblast. These columns are known as primary villi. At the same time, other migrating cells form into the exocoelomic cavity a new cavity named the secondary or definitive yolk sac, smaller than the primitive yolk sac.
The fetal origins hypothesis (differentiated from the Developmental Origins of Health and Disease hypothesis, which emphasizes environmental conditions both before and immediately after birth) proposes that the period of gestation has significant impacts on the developmental health and wellbeing outcomes for an individual ranging from infancy to adulthood.
The trivium (logic, grammar, and rhetoric) address the veracity, consistency, and beauty of the language of expression. The quadrivium (geometry, astronomy, arithmetic, and music) provide the intellectual content in need of expression. Thierry also wrote some commentaries on Boethius' De Trinitate.
Mammals during pregnancy can have one or more gestations at the same time, for example in a multiple birth. [2] The time interval of a gestation is called the gestation period. In obstetrics, gestational age refers to the time since the onset of the last menses, which on average is fertilization age plus two weeks. [3]
The embryological origin of granulosa cells remains controversial. In the 1970s, evidence emerged that the first cells to make contact with the oogonia were of mesonephric origin. It was suggested that mesonephric cells already closely associated with the oogonia proliferated throughout development to form the granulosa cell layer. [2] [3] [4]