Search results
Results from the WOW.Com Content Network
A mixture of CHIR99021 and valproic acid (FX-322) is claimed to increase the proliferation of inner ear stem cells, potentially allowing regrowth of the hair cells which are important for hearing, and are lost through chronic exposure to loud noises or as part of the aging process. [4] [5] [6]
The Gastruloid model system draws its origins from work by Marikawa et al.. [4] In that study, small numbers of mouse P19 embryonal carcinoma (EC) cells, were aggregated as embryoid bodies (EBs) and used to model and investigate the processes involved in anteroposterior polarity and the formation of a primitive streak region. [4]
SB431542 can also be used in combination with LDN193189, CHIR99021 and DAPT to transform astrocytes into neurons. [2] It is also commonly used for immunological studies, for instance as a TGF-β inhibitor to facilitate the generation of dendritic cells from peripheral blood monocytes .
Ex-SP #4423 5623: EMD GP9/GP9R: Operational, Niles Canyon Railway, Sunol, California Ex-SP #3189 5793: April 1957 EMD GP9 Operational at the Madison Railroad in Madison, Indiana as CMPA GP10 #3634 6051: EMD E9: Operational, California State Railroad Museum, Sacramento, California 6378: EMD F7A: Stored, serviceable, Niles Canyon Railway, Sunol ...
Glycogen synthase kinase 3 (GSK-3) is a serine/threonine protein kinase that mediates the addition of phosphate molecules onto serine and threonine amino acid residues. First discovered in 1980 as a regulatory kinase for its namesake, glycogen synthase (GS), [2] GSK-3 has since been identified as a protein kinase for over 100 different proteins in a variety of different pathways.
The topic of this article may not meet Wikipedia's general notability guideline. Please help to demonstrate the notability of the topic by citing reliable secondary sources that are independent of the topic and provide significant coverage of it beyond a mere trivial mention.
GSK2606414 is a drug which is the first selective inhibitor discovered for the enzyme protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK), which is involved in various processes relating to cancer and neurodegenerative disorders.
DAMGO ([D-Ala 2, N-MePhe 4, Gly-ol]-enkephalin) is a synthetic opioid peptide with high μ-opioid receptor specificity. It was synthesized as a biologically stable analog of δ-opioid receptor-preferring endogenous opioids, leu- and met-enkephalin. [1]