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Vitamin C megadosage is a term describing the consumption or injection of vitamin C (ascorbic acid) in doses well beyond the current United States Recommended Dietary Allowance of 90 milligrams per day, and often well beyond the tolerable upper intake level of 2,000 milligrams per day. [1]
Ascorbic acid efflux by embryos of dicot plants is a well-established mechanism of iron reduction and a step obligatory for iron uptake. [a] All plants synthesize ascorbic acid. Ascorbic acid functions as a cofactor for enzymes involved in photosynthesis, synthesis of plant hormones, as an antioxidant and regenerator of other antioxidants. [96]
In in vitro studies, the primary mechanism of high dosage intravenous ascorbic acid can be related to ascorbic acid's pro-oxidant activity, whereby hydrogen peroxide is formed. [ 17 ] [ 18 ] [ 19 ] In the extracellular fluid of cells, ascorbic acid dissociates into an ascorbate radical upon the reduction of transition metal ions, such as ferric ...
Scurvy is a deficiency disease (state of malnutrition) resulting from a lack of vitamin C (ascorbic acid). [1] Early symptoms of deficiency include weakness, fatigue, and sore arms and legs. [ 1 ] [ 2 ] Without treatment, decreased red blood cells , gum disease, changes to hair, and bleeding from the skin may occur.
ATC code A11 Vitamins is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.
An example of a mineral ascorbate drug is sodium ascorbate injections, as the acid form (ascorbic acid) of vitamin C is too acidic for injections). Ascorbate salts may be better tolerated by the human body than the corresponding weakly acidic ascorbic acid. Ascorbates are highly reactive antioxidants used as food preservatives. [2]
Many multivitamin formulas contain vitamin C, B 1, B 2, B 3, B 5, B 6, B 7, B 9, B 12, A, E, D 2 (or D 3), K, potassium, iodine, selenium, borate, zinc, calcium, magnesium, manganese, molybdenum, beta carotene, and/or iron. Multivitamins are typically available in a variety of formulas based on age and sex, or (as in prenatal vitamins) based on ...
Ascorbyl palmitate is an ester formed from ascorbic acid and palmitic acid creating a fat-soluble form of vitamin C. In addition to its use as a source of vitamin C, it is also used as an antioxidant food additive (E number E304). It is approved for use as a food additive in the EU, [1] the U.S., [2] Canada, [3] Australia, and New Zealand. [4]
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