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Ischemic colitis (also spelled ischaemic colitis) is a medical condition in which inflammation and injury of the large intestine result from inadequate blood supply . Although uncommon in the general population, ischemic colitis occurs with greater frequency in the elderly, and is the most common form of bowel ischemia .
Watershed area is the medical term referring to regions of the body, [1] that receive dual blood supply from the most distal branches of two large arteries, such as the splenic flexure of the large intestine. The term refers metaphorically to a geological watershed, or drainage divide, which separates adjacent drainage basins. For example, the ...
Although uncommon in the general population, ischemic colitis occurs with greater frequency in the elderly, and is the most common form of bowel ischemia. [ 43 ] [ 44 ] [ 45 ] Causes of the reduced blood flow can include changes in the systemic circulation (e.g. low blood pressure ), or local factors such as constriction of blood vessels or a ...
Mirikizumab, a drug currently approved by the Food and Drug Administration (FDA) for the treatment of ulcerative colitis, also sends Crohn's disease into clinical remission, new findings suggest.
Ulcerative colitis is an autoimmune disease characterized by T-cells infiltrating the colon. [43] No direct causes for UC are known, but factors such as genetics, environment, and an overactive immune system play a role. [1] UC is associated with comorbidities that produce symptoms in many areas of the body outside the digestive system.
On Wednesday, the FDA approved Eli Lilly And Co’s (NYSE:LLY) Omvoh (mirikizumab-mrkz) for moderately to severely active Crohn’s disease in adults. Omvoh is now approved in the U.S. for two ...
Primary vascular causes of bowel infarction, also known as mesenteric ischemia, are due to blockages in the arteries or veins that supply the bowel.Types of mesenteric ischemia are generally separated into acute and chronic processes, because this helps determine treatment and prognosis.
The splenic flexure is a watershed region as it receives dual blood supply from the terminal branches of the superior mesenteric artery and the inferior mesenteric artery, thus making it prone to ischemic damage in cases of low blood pressure because it does not have its own primary source of