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  2. Management of ME/CFS - Wikipedia

    en.wikipedia.org/wiki/Management_of_ME/CFS

    A systematic review found five RCTs to have assessed the effects of immunoglobulin treatment for ME/CFS; [42] of these, two RCTs showed an overall beneficial effect and two RCTs showed some positive results, although in one of the studies this was for physiological effects only. The largest of the RCTs found no effect for the treatment.

  3. Clinical descriptions of ME/CFS - Wikipedia

    en.wikipedia.org/wiki/Clinical_descriptions_of...

    The fatigue must have lasted for 6 months or longer, and be present at least 50% of the time; Other symptoms are possible, such as muscle pain, mood problems, or sleep disturbance; Conditions known to cause severe fatigue and some mental conditions exclude a diagnosis. Post-infectious fatigue syndrome also requires evidence of a prior infection ...

  4. Post-exertional malaise - Wikipedia

    en.wikipedia.org/wiki/Post-exertional_malaise

    Post-exertional malaise (PEM), sometimes referred to as post-exertional symptom exacerbation (PESE) [1] or post-exertional neuroimmune exhaustion (PENE), [2] is a worsening of symptoms that occurs after minimal exertion. It is the hallmark symptom of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and common in long COVID and ...

  5. Graded exercise therapy - Wikipedia

    en.wikipedia.org/wiki/Graded_exercise_therapy

    Graded exercise therapy (GET) is a programme of physical activity that starts very slowly and gradually increases over time, intended as a treatment for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Most public health bodies, including the CDC and NICE, consider it ineffective, and its safety is disputed.

  6. Pacing (activity management) - Wikipedia

    en.wikipedia.org/wiki/Pacing_(activity_management)

    Pacing has been used to help manage a wide variety of different illnesses and disabilities, including neuromuscular diseases like Charcot-Marie-Tooth disease (CMT), [7] rheumatoid or immune-mediated diseases like rheumatoid arthritis, [6] juvenile arthritis and fibromyalgia, ME/CFS, [8] Ehlers–Danlos syndromes (EDS), [3] and Long COVID.

  7. Myalgic encephalomyelitis/chronic fatigue syndrome - Wikipedia

    en.wikipedia.org/.../chronic_fatigue_syndrome

    ME/CFS causes debilitating fatigue, sleep problems, and post-exertional malaise (PEM, overall symptoms getting worse after mild activity). In addition, cognitive issues, orthostatic intolerance (dizziness or nausea when upright) or other physical symptoms may be present (see also § Diagnostic criteria ).

  8. Myalgia - Wikipedia

    en.wikipedia.org/wiki/Myalgia

    Myalgia or muscle pain is a painful sensation evolving from muscle tissue.It is a symptom of many diseases.The most common cause of acute myalgia is the overuse of a muscle or group of muscles; another likely cause is viral infection, especially when there has been no injury.

  9. Idiopathic chronic fatigue - Wikipedia

    en.wikipedia.org/wiki/Idiopathic_chronic_fatigue

    Prolonged fatigue is fatigue that persists for more than a month, and chronic fatigue is fatigue that lasts at least six consecutive months, which may be caused by a physical or psychological illness, or may be idiopathic (no known cause). [1] Chronic fatigue with a known cause is twice as common as idiopathic chronic fatigue. [6]