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  2. Schmidt reaction - Wikipedia

    en.wikipedia.org/wiki/Schmidt_reaction

    In organic chemistry, the Schmidt reaction is an organic reaction in which an azide reacts with a carbonyl derivative, usually an aldehyde, ketone, or carboxylic acid, under acidic conditions to give an amine or amide, with expulsion of nitrogen.

  3. Aminoaldehydes and aminoketones - Wikipedia

    en.wikipedia.org/wiki/Aminoaldehydes_and_aminoke...

    Because primary and secondary amines react with aldehydes and ketones, the most common variety of these aminocarbonyl compounds feature tertiary amines. Such compounds are produced by amination of α-haloketones and α-haloaldehydes. [1] Examples include cathinones, methadone, molindone, pimeclone, ferruginine, and tropinone.

  4. Leuckart reaction - Wikipedia

    en.wikipedia.org/wiki/Leuckart_reaction

    The Leuckart reaction is the chemical reaction that converts aldehydes or ketones to amines. The reaction is an example of reductive amination. [1] The reaction, named after Rudolf Leuckart, uses either ammonium formate or formamide as the nitrogen donor and reducing agent. It requires high temperatures, usually between 120 and 130 °C; for the ...

  5. Vilsmeier–Haack reaction - Wikipedia

    en.wikipedia.org/wiki/Vilsmeier–Haack_reaction

    The reaction of a substituted amide with phosphorus oxychloride gives a substituted chloroiminium ion (2), also called the Vilsmeier reagent. The initial product is an iminium ion (4b), which is hydrolyzed to the corresponding ketone or aldehyde during workup. [7] The Vilsmeier–Haack reaction

  6. Gewald reaction - Wikipedia

    en.wikipedia.org/wiki/Gewald_reaction

    The Gewald reaction (or the Gewald aminothiophene synthesis) is an organic reaction involving the condensation of a ketone (or aldehyde when R 2 = H) with a α-cyanoester in the presence of elemental sulfur and base to give a poly-substituted 2-amino-thiophene. [1] [2] The Gewald reaction. The reaction is named after the German chemist Karl ...

  7. Weinreb ketone synthesis - Wikipedia

    en.wikipedia.org/wiki/Weinreb_ketone_synthesis

    For these latter reactions, two equivalents of the incoming group add to form an alcohol rather than a ketone or aldehyde. This occurs even if the equivalents of nucleophile are closely controlled. Overaddition of nucleophiles. The Weinreb–Nahm amide has since been adopted into regular use by organic chemists as a dependable method for the ...

  8. Passerini reaction - Wikipedia

    en.wikipedia.org/wiki/Passerini_reaction

    The Passerini reaction is a chemical reaction involving an isocyanide, an aldehyde (or ketone), and a carboxylic acid to form a α-acyloxy amide. [1] [2] [3] [4] [5 ...

  9. Aldol reaction - Wikipedia

    en.wikipedia.org/wiki/Aldol_reaction

    The aldol reaction (aldol addition) is a reaction in organic chemistry that combines two carbonyl compounds (e.g. aldehydes or ketones) to form a new β-hydroxy carbonyl compound. Its simplest form might involve the nucleophilic addition of an enolized ketone to another: