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Because of its similarities to deep vein thrombosis (DVT), May–Thurner syndrome is rarely diagnosed amongst the general population. In this condition, the right iliac artery sequesters and compresses the left common iliac vein against the lumbar section of the spine, [5] resulting in swelling of the legs and ankles, pain, tingling, and/or numbness in the legs and feet. [6]
Decreased or no pulse in an arm or leg beyond the site of blockage [1] [2] Pain in the affected area [1] [2] Muscle spasm in the affected area [1] Numbness and tingling in an arm or leg [1] [2] Paleness [1] [2] of the skin of the arm or leg; Muscle weakness of an arm or leg, [1] [2] possibly to the grade of paralysis [2]
Swelling of the feet and ankle area. Painful burning, tingling, or numb sensations in the lower legs. Pain worsens and spreads after standing for long periods; pain is worse with activity and is relieved by rest. Electric shock sensations; Pain radiating up into the leg, [1] behind the shin, and down into the arch, heel, and toes
Peripheral neuropathy may be classified according to the number and distribution of nerves affected (mononeuropathy, mononeuritis multiplex, or polyneuropathy), the type of nerve fiber predominantly affected (motor, sensory, autonomic), or the process affecting the nerves; e.g., inflammation (), compression (compression neuropathy), chemotherapy (chemotherapy-induced peripheral neuropathy).
Other skin changes can include swelling, stiffness, or cold temperature. [9] Pulselessness: A lack of pulse rarely occurs in patients, as pressures that cause compartment syndrome are often lower than arterial pressures. [5] Absent pulses occur only with arterial injury or late-stage compartment syndrome, when pressures are very high. [5]
The condition is commonly associated with vascular and cardiac changes associated with aging but can be caused by many other conditions, including congestive heart failure, kidney failure, liver cirrhosis, portal hypertension, trauma, alcoholism, altitude sickness, pregnancy, hypertension, sickle cell anemia, a compromised lymphatic system or merely long periods of time sitting or standing ...
Or cold hands that come with other symptoms, such as joint pain, a new rash, weight loss, night sweats (as seen in connective tissue/autoimmune diseases), pallor, weakness, shortness of breath ...
Weakness or numbness may occur in various parts of the affected leg and foot. [3] About 90% of sciatica is due to a spinal disc herniation pressing on one of the lumbar or sacral nerve roots. [4] Spondylolisthesis, spinal stenosis, piriformis syndrome, pelvic tumors, and pregnancy are other possible causes of sciatica. [3]
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