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Omega-3-acid ethyl esters are used in addition to changes in diet to reduce triglyceride levels in adults with severe (≥ 500 mg/dL) hypertriglyceridemia. [3] In the European Union and other major markets outside the US, omega-3-acid ethyl esters are indicated for hypertriglyceridemia by itself, or in combination with a statin for people with mixed dyslipidemia.
There are other omega−3 fish oil based drugs on the market that have similar uses and mechanisms of action. [8] Omega−3-acid ethyl esters (brand names Omarcor or Lovaza, [9] Omtryg, [10] and as of March 2016, four generic versions). [11] Ethyl eicosapentaenoic acid (Vascepa, and 1 generic as ethyl icosapent) [12]
In Denmark it is a bulk manufacturer of omega-3 products with a manufacturing plant in Kalundborg. It was acquired by BASF in 2014. [1] Pronova BioPharma ASA had its roots in Norway's codfish liver oil industry. The company was founded in 1991 as a spinout from the JC Martens company, which in turn was founded in 1838 in Bergen, Norway. [2]
There are other omega−3 fish-oil based drugs on the market that have similar uses and mechanisms of action: [12] [7] [13] Omega-3-acid ethyl esters (brand names Omacor [renamed Lovaza in the U.S. to avoid confusion with Amicar and Omtryg]), [14] [15] and as of March 2016, four generic versions [16] [17]
Brand Name(s) Generic Name Sales Q1 2014 Sales ($000) ... Omega-3 fatty acid ethyl esters: 258,177: 2.90%: GlaxoSmithKline: Cholesterol: Jun-2001: Mon-20XX 60 ...
An omega−3 fatty acid is a fatty acid with multiple double bonds, where the first double bond is between the third and fourth carbon atoms from the end of the carbon atom chain. "Short-chain" omega−3 fatty acids have a chain of 18 carbon atoms or less, while "long-chain" omega−3 fatty acids have a chain of 20 or more.
Omega−3 fatty acids are important for normal metabolism. [ 2 ] Mammals are unable to synthesize omega−3 fatty acids, but can obtain the shorter-chain omega−3 fatty acid ALA (18 carbons and 3 double bonds) through diet and use it to form the more important long-chain omega−3 fatty acids, EPA (20 carbons and 5 double bonds) and then from ...
Pages in category "Fatty acid esters" The following 34 pages are in this category, out of 34 total. ... Omega-3-acid ethyl esters; P. Polyglycerol polyricinoleate; R ...
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