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  2. Gastrointestinal bleeding - Wikipedia

    en.wikipedia.org/wiki/Gastrointestinal_bleeding

    Bleeding is typically divided into two main types: upper gastrointestinal bleeding and lower gastrointestinal bleeding. [2] Causes of upper GI bleeds include: peptic ulcer disease, esophageal varices due to liver cirrhosis and cancer, among others. [3] Causes of lower GI bleeds include: hemorrhoids, cancer, and inflammatory bowel disease among ...

  3. Hepatorenal syndrome - Wikipedia

    en.wikipedia.org/wiki/Hepatorenal_syndrome

    HRS can affect individuals with cirrhosis, severe alcoholic hepatitis, or liver failure, and usually occurs when liver function deteriorates rapidly because of a sudden insult such as an infection, bleeding in the gastrointestinal tract, or overuse of diuretic medications. HRS is a relatively common complication of cirrhosis, occurring in 18% ...

  4. Alcoholic liver disease - Wikipedia

    en.wikipedia.org/wiki/Alcoholic_liver_disease

    Cirrhosis is a late stage of serious liver disease marked by inflammation (swelling), fibrosis (cellular hardening) and damaged membranes preventing detoxification of chemicals in the body, ending in scarring and necrosis (cell death). [11] Between 10% and 20% of heavy drinkers will develop cirrhosis of the liver (NIAAA, 1993).

  5. Cirrhosis - Wikipedia

    en.wikipedia.org/wiki/Cirrhosis

    Liver cirrhosis makes it hard for blood to flow in the portal venous system. [39] This resistance creates a backup of blood and increases pressure. [39] This results in portal hypertension. Effects of portal hypertension include: Ascites is a build-up of fluid in the peritoneal cavity in the abdomen [40] An enlarged spleen in 35–50% of cases [6]

  6. Long-term effects of alcohol - Wikipedia

    en.wikipedia.org/wiki/Long-term_effects_of_alcohol

    A study of 4,465 subjects in India confirmed the association of alcohol consumption with coronary risk in men. Compared to lifetime abstainers, alcohol users had higher blood sugar (2 mg/dl), blood pressure (2 mm Hg) levels, and the high-density lipoprotein cholesterol (HDL-C) levels (2 mg/dl) and significantly higher tobacco use (63% vs. 21%).

  7. Hepatitis - Wikipedia

    en.wikipedia.org/wiki/Hepatitis

    Biopsy is typically not the initial diagnostic test because it is invasive and is associated with a small but significant risk of bleeding that is increased in people with liver injury and cirrhosis. [70] Blood testing includes liver enzymes, serology (i.e. for autoantibodies), nucleic acid testing (i.e. for hepatitis virus DNA/RNA), blood ...

  8. Liver disease - Wikipedia

    en.wikipedia.org/wiki/Liver_disease

    [47] [48] Alcohol-related liver disease accounts for about 4.5% of liver-related deaths globally, underscoring the substantial burden of alcohol misuse. [49] Viral hepatitis, primarily hepatitis B and hepatitis C, remains a leading cause of liver cirrhosis and liver cancer worldwide, despite advances in antiviral therapies and vaccination ...

  9. Metabolic dysfunction–associated steatotic liver disease

    en.wikipedia.org/wiki/Metabolic_dysfunction...

    The condition is strongly associated with or caused by type 2 diabetes, insulin resistance, and metabolic syndrome (defined as at least three of the five following medical conditions: abdominal obesity, high blood pressure, high blood sugar, high serum triglycerides, and low serum high-density lipoprotein).

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