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  2. ALS - Wikipedia

    en.wikipedia.org/wiki/ALS

    The lifetime risk of developing ALS is 1:350 for European men and 1:400 for European women. Men have a higher risk mainly because spinal-onset ALS is more common in men than women. [63] The number of those with ALS in the United States in 2015 was 5.2 people per 100,000, and was higher in whites, males, and people over 60 years old. [124]

  3. Corticobasal degeneration - Wikipedia

    en.wikipedia.org/wiki/Corticobasal_degeneration

    Although men and women present with the disease, some analysis has shown a predominant appearance of CBD in women. Current calculations suggest that the prevalence of CBD is approximately 4.9 to 7.3 per 100,000 people. CBD research has been limited by the rarity of the disease and the lack of research criteria.

  4. List of people with motor neuron disease - Wikipedia

    en.wikipedia.org/wiki/List_of_people_with_motor...

    Public awareness of the disease gained prominence upon the diagnosis of baseball player Lou Gehrig, whose name would become an alternative title for the disease. Astrophysicist Stephen Hawking, whose ALS was diagnosed in 1963, had the disease for 55 years, the longest recorded time one had the disease. He died at the age of 76 in 2018.

  5. Woman, 29, Discovers Through Genetic Testing She Will ... - AOL

    www.aol.com/woman-29-discovers-genetic-testing...

    The 29-year-old was told by doctors she has a 100% chance of having ALS someday, too; now, she is documenting both her new reality and her ongoing fertility journey online

  6. Woman diagnosed with ALS at 27 shares how she thinks ... - AOL

    www.aol.com/news/woman-diagnosed-als-27-shares...

    Learning she had ALS at 27 felt tough. But woman starts organization to help other young women with ALS. Hopes

  7. Amylyx Pharma to remove ALS drug from US, Canada markets - AOL

    www.aol.com/news/amylyx-pharma-remove-als-drug...

    The ALS drug, branded Relyvrio, was approved in 2022 after lobbying by patient groups who pointed to limited options to treat the potentially fatal disease. ALS causes progressive paralysis and ...

  8. Motor neuron diseases - Wikipedia

    en.wikipedia.org/wiki/Motor_neuron_diseases

    Motor neuron disease can affect either upper motor neurons (UMNs) or lower motor neurons (LMNs). Motor neuron disease describes a collection of clinical disorders, characterized by progressive muscle weakness and the degeneration of the motor neuron on electrophysiological testing. The term "motor neuron disease" has varying meanings in ...

  9. Genetics of amyotrophic lateral sclerosis - Wikipedia

    en.wikipedia.org/wiki/Genetics_of_amyotrophic...

    [4] [5] ALS has an oligogenic mode of inheritance, meaning that mutations in two or more genes are required to cause disease. [6] C9orf72 is the most common gene associated with ALS, causing 40% of familial cases of ALS, as well as a small percentage of sporadic cases; [7] it also causes about 25% of familial cases of frontotemporal dementia. [6]

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