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Chronic spontaneous urticaria, despite its cause being unknown, is linked to a higher prevalence of autoimmune diseases, and is often worsened by triggers like stress, infections, certain foods, or nonsteroidal anti-inflammatory drugs. The hives and angioedema seen in CSU is thought to be linked to the degranulation of skin mast cells.
However, the understanding of urticaria as an autoimmune condition is a relatively recent development in medical history. [14] The term autoimmune urticaria refers to a subset of chronic spontaneous urticaria (CSU) cases where the immune system appears to play a significant role. This understanding began to evolve in the mid to late 20th ...
Hives including chronic spontaneous hives can be a complication and symptom of a parasitic infection, such as blastocystosis and strongyloidiasis among others. [ 11 ] The rash that develops from poison ivy , poison oak , and poison sumac contact is commonly mistaken for urticaria.
Autoimmune urticaria: Skin IgG against IgE or IgE receptor: Probable Not well established [5] [6] Bullous pemphigoid: Skin Anti-BP180, Anti-BP230 Confirmed 6-30 per 100,000 (mostly older adults) [7] Cicatricial pemphigoid: Mucous membranes, sometimes skin Anti-BP180, Anti-BP230 Confirmed Rare [8] Dermatitis herpetiformis: Skin Anti-tissue ...
Urticaria is a vascular reaction of the skin characterized by the appearance of wheals. Angioedema , which can occur alone or with urticaria, is characterized by a well-defined, edematous swelling that involves subcutaneous tissues, abdominal organs, and/or upper airway.
Physical urticaria is a distinct subgroup of urticaria (hives) that are induced by an exogenous physical stimulus rather than occurring spontaneously. [1] There are seven subcategories that are recognized as independent diseases. [2] [3] Physical urticaria is known to be painful, itchy and physically unappealing; it can recur for months to ...
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When an allergen is ingested, a dispersed form of wheal-and-flare reaction, known as urticaria or hives will appear when the allergen enters the bloodstream and eventually reaches the skin. [ 37 ] [ 38 ] The way our skin reacts to different allergens gives allergists the upper hand and allows them to test for allergies by injecting a very small ...