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The main drawback of modern HDE for prostate cancer is a high incidence of gynecomastia of about 40 to 77%, although it is generally only mildly or modestly discomforting. [54] In addition, prophylactic irradiation of the breasts can be used to prevent it and has minimal side effects, mostly consisting of temporary skin discoloration. [54]
Examples of such side effects include breast tenderness and enlargement, nausea, bloating, edema, headache, and melasma. [15] [62] High-dose estrogen therapy with estradiol valerate injections may also cause an increased risk of thromboembolism, changes in blood lipid profile, increased insulin resistance, and increased levels of prolactin. [62]
List of side effects of estradiol which may occur as a result of its use or have been associated with estrogen and/or progestogen therapy includes: [1] [2]. Gynecological: changes in vaginal bleeding, dysmenorrhea, increase in size of uterine leiomyomata, vaginitis including vaginal candidiasis, changes in cervical secretion and cervical ectropion, ovarian cancer, endometrial hyperplasia ...
Examples of such side effects include breast tenderness and enlargement, nausea, vomiting, bloating, edema, headache, migraine, and melasma. [54] [55] High-dose estrogen therapy with estradiol cypionate injections may also cause an increased risk of thromboembolism, changes in blood lipid profile, increased insulin resistance, and increased ...
The exact cause of melasma is unknown, says Dr. Robert Finney, MD, a board-certified dermatologist in New York City. But it’s believed to result from the skin’s pigment-producing cells being ...
Estradiol is used in menopausal hormone therapy to prevent and treat moderate to severe menopausal symptoms such as hot flashes, vaginal dryness and atrophy, and osteoporosis (bone loss). [11] As unopposed estrogen therapy (using estrogen alone without progesterone) increases the risk of endometrial hyperplasia and endometrial cancer in women ...
Shop the best melasma treatments and serums for hyperpigmentation. Expert-recommended products include La Roche Posay, Neutrogena, SkinCeuticals and more. 11 dermatologist-approved melasma ...
Ahead, everything you need to know about getting rid of melasma, plus the best at-home products and in-office treatments for fading it fast according to derms.