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This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs ... plaque psoriasis, psoriatic arthritis, ankylosing ...
Efalizumab (brand name Raptiva, Genentech, Merck Serono) is a formerly available medication designed to treat autoimmune diseases, originally marketed to treat psoriasis. As implied by the suffix -zumab , it is a recombinant humanized monoclonal antibody administered once weekly by subcutaneous injection .
These medications are generally well-tolerated, and limited long-term outcome data have demonstrated biologics to be safe for long-term use in moderate to severe plaque psoriasis. [ 99 ] [ 101 ] However, due to their immunosuppressive actions, biologics have been associated with a small increase in the risk for infection.
The first medical use of fumaric acid was described in 1959 by Walter Schweckendiek, a German chemist, [15] and was a topical formulation for psoriasis. The Swiss company Fumapharm eventually brought Fumaderm, an oral formulation of dimethyl fumarate (along with some monoesters) to market for psoriasis in Germany in 1994. [16] [17] [18]
Adalimumab, sold under the brand name Humira and others, is a disease-modifying antirheumatic drug and monoclonal antibody used to treat rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease, ulcerative colitis, plaque psoriasis, hidradenitis suppurativa, and uveitis.
The Nizoral Scalp Psoriasis Shampoo and Conditioner is another great product for treating scalp psoriasis. This shampoo provides fast-acting relief to itchy, dry, and flaky areas on the scalp.
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