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Pathology sample of a mucinous tumor of the ovary. It is well documented that malignancy may be only focally present in mucinous neoplasms of the ovary, so thorough sampling is imperative. The major distinguishing features of mucinous tumors are that the tumors are filled with a mucus-like material, which gives them their name; this mucus is ...
Tumor of the ovary vary remarkably as they may arise from any of the 3 cell types of the normal ovary. Ovarian tumors are classified according to the histology of the tumor, obtained in a pathology report. Histology dictates many aspects of clinical treatment, management, and prognosis. The most common forms are:
They are common neoplasms with a strong tendency to occur bilaterally, and they account for approximately a quarter of all ovarian tumors. Rarely, serous tumors arise from within the uterus, notably uterine serous carcinoma , which typically arises in postmenopausal women.
These ovarian tumors are usually multi-septated, cystic masses with thin walls. They also contain varying amounts of solid tissue which consists of proliferating stromal tissue, papillae, or malignant tumor cells. Benign mucinous cystadenomas compose 80% of mucinous ovarian tumors [2] and 20–25% of benign ovarian tumors overall. The peak ...
A mucinous neoplasm (also called colloid neoplasm) is an abnormal and excessive growth of tissue with associated mucin (a fluid that sometimes resembles thyroid colloid). It arises from epithelial cells that line certain internal organs and skin, and produce mucin (the main component of mucus ).
Histopathology of lining of a benign mucinous tumor of the ovary. Benign mucinous ovarian tumors consist of simple, nonstratified columnar epithelium with basally-located hyperchromatic nuclei and resemble gastric foveolar epithelium. [14] Mucinous tumors: Closely resemble their serous counterparts but unlikely to be bilateral
Serous ovarian cancer is the most common type of epithelial ovarian cancer and it accounts for about two-thirds of cases of epithelial ovarian cancer. [28] Low-grade serous carcinoma is less aggressive than high-grade serous carcinomas, though it does not typically respond well to chemotherapy or hormonal treatments. [ 28 ]
n/a Ensembl ENSG00000181143 n/a UniProt Q8WXI7 n/a RefSeq (mRNA) NM_024690 NM_001401501 n/a RefSeq (protein) NP_078966 n/a Location (UCSC) Chr 19: 8.85 – 8.98 Mb n/a PubMed search n/a Wikidata View/Edit Human Mucin-16 (MUC-16) also known as Ovarian cancer-related tumor marker CA125 is a protein that in humans is encoded by the MUC16 gene. MUC-16 is a member of the mucin family glycoproteins ...