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The following is a list of antibiotics.The highest division between antibiotics is bactericidal and bacteriostatic.Bactericidals kill bacteria directly, whereas bacteriostatics prevent them from dividing.
An antibiotic is a type of antimicrobial substance active against bacteria.It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention of such infections.
The antimicrobial spectrum of an antibiotic can be determined by testing its antimicrobial activity against a wide range of microbes in vitro. Nonetheless, the range of microorganisms which an antibiotic can kill or inhibit in vivo may not always be the same as the antimicrobial spectrum based on data collected in vitro. [2] [5]
Antimicrobial use has been common practice for at least 2000 years. Ancient Egyptians and ancient Greeks used specific molds and plant extracts to treat infection. [5]In the 19th century, microbiologists such as Louis Pasteur and Jules Francois Joubert observed antagonism between some bacteria and discussed the merits of controlling these interactions in medicine. [6]
In order to guide appropriate use of antibiotics and prevent the evolution and spread of antimicrobial resistance, diagnostic tests that provide clinicians with timely, actionable results are needed. Acute febrile illness is a common reason for seeking medical care worldwide and a major cause of morbidity and mortality.
The discovery of antimicrobial agents contributed significantly to UTI management during the 20th century. Nitrofurantoin emerged as the first practical and safe urinary antimicrobial agent, but it was with limited spectrum of activity. [48] Subsequently, in the 1970s, beta-lactam antibiotics and TMP/SMX became available for UTI therapy. [48]
At this time the optimal metrics to benchmark antimicrobial use are still controversial: To measure unit of antimicrobials consumed, one can use 'Days Of Therapy' (DOT) or Defined Daily Dose (DDD). The former is more commonly used in the US, the latter is more commonly used in Europe. The 2016 IDSA/SHEA guidelines recommend the use of DOT. [37]
ASM Microbe, a combination of what was formerly the ASM General Meeting and the Interscience Conference on Antimicrobial Agents and Chemotherapy, includes sessions in eight specialty tracks: Antimicrobial Agents and Resistance; Applied and Environmental Science; Clinical Infections and Vaccines; Clinical and Public Health Microbiology