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  2. Sildenafil - Wikipedia

    en.wikipedia.org/wiki/Sildenafil

    Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [4] [8] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon. [9] It is unclear if it is effective for treating sexual dysfunction in females. [8]

  3. Things You Probably Don't Know About Viagra (Like What ... - AOL

    www.aol.com/things-probably-dont-know-viagra...

    Viagra is definitely not an appropriate first-line treatment for Raynaud’s phenomenon, but in situations where more common medications have failed, it could be an option. Halfpoint/istockphoto ...

  4. PDE5 inhibitor - Wikipedia

    en.wikipedia.org/wiki/PDE5_inhibitor

    PDE5 inhibitors have been used as a second line therapy in severe cases of Raynaud phenomenon when it is related to systemic sclerosis per The European Society for Vascular Medicine guidelines. [3] Sildenafil, the prototypical PDE5 inhibitor, was originally discovered during the search of a novel treatment for angina.

  5. cGMP-specific phosphodiesterase type 5 - Wikipedia

    en.wikipedia.org/wiki/CGMP-specific_phosphodi...

    Sildenafil (marketed as Viagra) was the first PDE5 inhibitor on the market. Originally created as a treatment for high blood pressure in 1989, it was found to have a secondary use as an effective PDE5 inhibitor, enabling men who use it to gain stronger erections after arousal. The FDA approved Viagra on March 27, 1998. [20]

  6. Cialis vs. Viagra: How Are They Different? - AOL

    www.aol.com/cialis-vs-viagra-different-175700354...

    How Cialis and Viagra Work. Used by millions of men ... Viagra was approved by the FDA as a treatment for ED in 1998. ... It came onto the market a little later than Viagra, first receiving ...

  7. Is Sildenafil Safe for This Common Male Problem? - AOL

    www.aol.com/sildenafil-safe-common-male-problem...

    For most men, sildenafil is a safe and effective treatment for ED when used as prescribed. However, like all drugs, it comes with its own set of potential side effects and interactions.

  8. Facing Off Against Counterfeit Online Pharmacies: Pfizer ...

    www.aol.com/news/2013-05-06-facing-off-against...

    Viagra was the first oral ED medication, approved by the U.S. Food and Drug Administration in 1998. Viagra has been studied for more than 15 years in more than 136 completed and ongoing clinical ...

  9. Your ED Pill Guide: Everything You Need to Know Before ... - AOL

    www.aol.com/ed-pill-guide-everything-know...

    Whether you’re one of the 30 million men who have (ED) or not, you’ve almost certainly heard of Viagra. Maybe you even know about other ED medications, like Levitra or Stendra or Cialis, too.