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A549 has also been employed in viral research and associated protein expression changes as a consequence of viral infection. [10] Although A549 is a cancer cell line, it has also been studied for its response to tuberculosis, specifically the production of chemokines as it is induced by the invading bacteria. [11]
An immortalised cell line is a population of ... A549 cells – derived from a cancer patient lung ... a widely used human cell line isolated from cervical cancer ...
The Atlas is part of the genome project and participates in research on cancer epidemiology. The Atlas is accessed by: 1- researchers in cytogenetics, molecular biology, cell biology; 2- clinicians, haematologists, cytogeneticists, pathologists, from the university hospitals, indeed, but also from general hospitals where the Atlas is one of the ...
Among the products of the program is the Azimuth reference datasets for single-cell RNA seq data [2] [3] and the ASCT+B Reporter, a visualization tool for anatomical structures, cell types and biomarkers. [4] [5] Millitomes are used to create uniformly sized tissue blocks that match the shape and size of organs from HuBMAP's 3D Reference Object ...
A549 cells share the same characteristics with the alveolar type II cells. This are type II pneumocytes crucial for lung homeostasis, and regeneration upon damage. For research purposes to unravel different molecular mechanisms leading to lung diseases, A549 cells serves as a good model to which translational research can be relied upon.
A 61st cell line, MDA-N, has been confirmed to being derived from the misclassified MDA-MB-435 cell line. [7] So it is also misclassified, really being a melanoma cell line, but as of 6 January 2018 the official website still lists it as breast cancer cell line. [1] This cell line is not available as of 6 January 2018. [1] The International ...
The Cancer Genome Atlas (TCGA) is a project to catalogue the genomic alterations responsible for cancer using genome sequencing and bioinformatics. [1] [2] The overarching goal was to apply high-throughput genome analysis techniques to improve the ability to diagnose, treat, and prevent cancer through a better understanding of the genetic basis of the disease.
The Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer is a free-access database devoted to chromosomes, genes, and cancer. It was first published in 1983 as a book named "Catalog of Chromosome aberrations in Cancer" in the Journal of Cytogenetics and Cell Genetics, containing 3,844 cases. [ 1 ]