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Sodium thiosulfate, also spelled sodium thiosulphate, is used as a medication to treat cyanide poisoning, pityriasis versicolor, and to decrease side effects from cisplatin. [ 3 ] [ 4 ] [ 5 ] For cyanide poisoning, it is often used after the medication sodium nitrite and is typically only recommended for severe cases.
Thiosulfate: The evidence for sodium thiosulfate's use is based on animal studies and case reports: the small quantities of cyanide present in dietary sources and in cigarette smoke are normally metabolized to relatively harmless thiocyanate by the mitochondrial enzyme rhodanese (thiosulfate cyanide sulfurtransferase), which uses thiosulfate as ...
Sodium thiosulfate (sodium thiosulphate) is an inorganic compound with the formula Na 2 S 2 O 3 ·(H 2 O) x. Typically it is available as the white or colorless pentahydrate (x = 5), which is a white solid that dissolves well in water. The compound is a reducing agent and a ligand, and these properties underpin its applications. [2]
For example, the LD50 of potassium cyanide alone is 11 mg/kg, whereas it is 21 mg/kg in the presence of sodium nitrite, giving a protective index of 1.91. The LD50 of potassium cyanide in the presence of sodium thiosulfate is 35 mg/kg, giving a protective index of 3.2.
Sodium nitrite/sodium thiosulfate, sold under the brand name Nithiodote, is a fixed-dose combination medication used as an antidote for cyanide poisoning. [1] It contains sodium thiosulfate and sodium nitrite. [1] It is given by intravenous infusion into a vein. [1] It was approved for medical use in the United States in January 2011. [2]
"If you are feeling bloated and sluggish after the holidays, it is most likely water retention from eating higher-sodium and higher-sugar foods, along with alcohol and less overall activity," New ...
Not all sodium is bad for you. “Sodium is a mineral known as an electrolyte that is needed for many functions in our bodies,” dietitian Tami Best tells Yahoo Life. “We need it for fluid ...
Nutrition (Per tbsp): Calories: 60 Fat: 6 g (Saturated Fat: 2 g) Sodium: 90 mg Carbs: 0 g (Fiber: 0 g, Sugar: 0 g) Protein: 0 g. This brand is probably most synonymous with substitute butter, and ...
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