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The hCG test can be used to screen for uterus cancer, or a molar pregnancy, which is when there is abnormal placental growth in the uterus. [9] The hCG test can also be done after a miscarriage to ensure that a molar pregnancy is not present. In men, the hCG test can be used to screen for the presence of testicular cancer. [9]
A pregnancy test may be used to detect high levels of chorionic gonadotropin; however, the first sign of testicular cancer is usually a painless lump. [28] Note that only about 25% of seminomas have elevated chorionic gonadotropin, so a pregnancy test is not very sensitive for making out testicular cancer.
Human chorionic gonadotropin is a glycoprotein composed of 237 amino acids with a molecular mass of 36.7 kDa, approximately 14.5kDa αhCG and 22.2kDa βhCG. [4]It is heterodimeric, with an α (alpha) subunit identical to that of luteinizing hormone (LH), follicle-stimulating hormone (FSH), thyroid-stimulating hormone (TSH), and a β (beta) subunit that is unique to hCG.
Pregnancy tests fall into two categories: at-home urine tests and the in-office blood test. At-home urine tests have different thresholds for the level of hCG they’re looking for, Dr. Ahmad says.
The two primary methods are testing for the female pregnancy hormone (human chorionic gonadotropin (hCG)) in blood or urine using a pregnancy test kit, and scanning with ultrasonography. [1] Testing blood for hCG results in the earliest detection of pregnancy. [2] Almost all pregnant women will have a positive urine pregnancy test one week ...
In the testis pure embryonal carcinoma is also uncommon, and accounts for approximately ten percent of testicular germ cell tumours. However, it is present as a component of almost ninety percent of mixed nonseminomatous germ cell tumours. The average age at diagnosis is 31 years, and typically presents as a testicular lump which may be painful.
Choriocarcinoma of the placenta during pregnancy is preceded by: hydatidiform mole (50% of cases) spontaneous abortion (20% of cases) ectopic pregnancy (2% of cases) normal term pregnancy (20–30% of cases) hyperemesis gravidarum; Rarely, choriocarcinoma occurs in primary locations other than the placenta; very rarely, it occurs in testicles.
If she is the inventor of the first at-home pregnancy test she is certainly worthy of one. In researching the patents referred to in the article - "She was granted two U.S. patents: 3,579,306 and 215,774" - I cannot find US patent 215,774 or any reference to Margaret Crane on any other patent than 3,579,306.