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Rather, the question should be “Does B12 deficiency cause weight gain” as some evidence suggests low levels of B12 may be linked to weight gain and obesity.
[55] [56] [57] A long-term study where vitamin B 12 was supplemented across a period of 10 years, led to lower levels of weight gain in overweight or obese individuals (p < 0.05). [58] There are several mechanisms which may explain the relationship between obesity and decreased vitamin B 12 status.
“A B12 deficiency can cause physical and neurological symptoms, and research is also growing to support that it can also cause psychological issues as well,” says Shapiro. ... Weight loss ...
A B12 deficiency can cause issue ranging from exhaustion to neurological problems. ... weight loss. infertility. tingly hands and feet due to nerve problems. balance issues. depression.
Both low-dose (2 mg/day) and high-dose CPA combined with an estrogen have been associated with vitamin B12 deficiency in women in some small studies. [268] [269] [7] Vitamin B12 deficiency in turn has been associated with depression, anxiety, irritability, and fatigue due to depletion of central monoamine neurotransmitters.
[6] [15] [26] Vitamin B 12 deficiency can also cause symptoms of mania and psychosis. [27] [28] Among other problems, weakened immunity, reduced fertility and interruption of blood circulation in women may occur. [29] The main type of vitamin B12 deficiency anemia is pernicious anemia, [30] characterized by a triad of symptoms:
10. You're taking medications that cause weight gain "Certain medications can induce weight gain or hinder weight loss by altering hormones, changing appetite, or causing water retention," says Costa.
Pernicious anemia is the most common cause of clinically evident vitamin B 12 deficiency worldwide. [14] Pernicious anemia due to autoimmune problems occurs in about one per 1000 people in the US. Among those over the age of 60, about 2% have the condition. [ 8 ]
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