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Mutations in the COL11A2 gene have been shown to cause hearing loss without other signs or symptoms (nonsyndromic deafness autosomal dominant) in two large families.One family carries a mutation that substitutes the amino acid cysteine (a building block of proteins) for the amino acid arginine at position 549 (written as Arg549Cys) in the alpha 2 chain of type XI collagen.
Natural skin care uses topical creams and lotions made of ingredients available in nature. [1] Much of the recent literature reviews plant-derived ingredients, which may include herbs , roots , flowers and essential oils , [ 2 ] [ 3 ] [ 4 ] but natural substances in skin care products include animal-derived products such as beeswax , and minerals.
A systematic review examined the benefits and clinical efficacy of routine skin care activities, such as washing, bathing, and applying lotions, in acute and long-term care adult settings. The study led to a proposed 2-step program targeting adults with intact or preclinically damaged skin. [13]
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