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Enalapril, sold under the brand name Vasotec among others, is an ACE inhibitor medication used to treat high blood pressure, diabetic kidney disease, and heart failure. [5] For heart failure, it is generally used with a diuretic , such as furosemide . [ 6 ]
Common treatments for DCM in dogs include: 1. Pimobendan tablets Pimobendan tablets help the heart to pump more effectively and are fairly safe. 2. ACE inhibitors (benazepril, enalapril etc)
enalapril – ACE-inhibitor used to treat high blood pressure and heart failure; enrofloxacin – Broad spectrum antibiotic (Gram-positive and -negative) -- not recommended for streptococci, or anaerobic bacteria; equine chorionic gonadotropin – gonadotropic hormone used to induce ovulation in livestock prior to artificial insemination
Enalaprilat is the active metabolite of enalapril. It is the first dicarboxylate-containing ACE inhibitor and was developed partly to overcome these limitations of captopril. The thiol functional group of captopril was replaced with a carboxylic acid group, but additional modifications were required to achieve a potency similar to captopril.
Enalapril/hydrochlorothiazide, sold under the brand name Vaseretic among others, is a fixed-dose combination medication used for the treatment of hypertension (high blood pressure). [2] It contains enalapril , an angiotensin converting enzyme inhibitor , and hydrochlorothiazide a diuretic . [ 2 ]
On January 10, 2020, The US Food and Drug Administration (FDA) announced a voluntary recall of 100 mg Lamotrigine (Generic for Lamictal) tablets manufactured by Taro Pharmaceuticals USA due to cross-contamination with Enalapril Maleate at a Taro Pharmaceuticals manufacturing facility. [12] [13]
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