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In pharmacology, the term ceiling effect refers to the property of increasing doses of a given medication to have progressively smaller incremental effect (an example of diminishing returns). Mixed agonist-antagonist opioids , such as nalbuphine , serve as a classic example of the ceiling effect; increasing the dose of a narcotic frequently ...
Low-threshold treatment programs are harm reduction-based health care centers targeted towards people who use substances. [1] " Low-threshold" programs are programs that make minimal demands on the patient, offering services without attempting to control their intake of drugs, and providing counselling only if requested.
Turtlestitch is derived from educational programming languages such as Logo, Scratch and Snap! using the same jigsaw style programming paradigm [2] which offers simplicity suitable for novices but has powerful features, described as ‘low threshold, high ceiling’ by Seymour Papert. Its microworld is a turtle representing the needle of a ...
Loop diuretics usually have a ceiling effect whereby doses greater than a certain maximum amount will not increase the clinical effect of the drug. Also, there is a threshold minimum concentration of loop diuretics that needs to be achieved at the thick ascending limb to enable the onset of abrupt diuresis. [10]
Threshold limit value − time-weighted average (TLV-TWA): The average exposure on the basis of a 8 hours per day, 40 hours per week work schedule. Threshold limit value − short-term exposure limit (TLV-STEL): A 15-minute TWA exposure that should not be exceeded at any time during a workday, even if the 8-hour TWA is within the TLV-TWA.
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The "ceiling effect" is one type of scale attenuation effect; [1] the other scale attenuation effect is the "floor effect". The ceiling effect is observed when an independent variable no longer has an effect on a dependent variable , or the level above which variance in an independent variable is no longer measurable. [ 2 ]
The expert panel believes that the Ultra-Low-Level Radiation laboratory is the only experiment that can explore with authority and confidence the effects of low-level radiation; that it can confirm or discard the various radiobiological effects proposed at low radiation levels e.g. LNT, threshold and radiation hormesis. [69]