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An outcome measure, endpoint, effect measure or measure of effect is a measure within medical practice or research, (primarily clinical trials) which is used to assess the effect, both positive and negative, of an intervention or treatment. [1] [2] Measures can often be quantified using effect sizes. [3]
Outcome measurement is therefore an important but neglected tool in improving quality of healthcare provision. It has been argued that it is vital that the patient has been meaningfully involved in decisions about whether or not to embark on an intervention (e.g. a test, an operation, a medicine).
The Patient-Reported Outcomes Measurement Information System [1] (PROMIS) provides clinicians and researchers access to reliable, valid, and flexible measures of health status that assess physical, mental, and social well–being from the patient perspective. PROMIS measures are standardized, allowing for assessment of many patient-reported ...
Clinical endpoints or clinical outcomes are outcome measures referring to occurrence of disease, symptom, sign or laboratory abnormality constituting a target outcome in clinical research trials. The term may also refer to any disease or sign that strongly motivates withdrawal of an individual or entity from the trial, then often termed a ...
The Core Outcome Measures in Effectiveness Trials (COMET) group is an international collaboration that provides extensive methodological support to all groups developing core outcome sets. [11] COMET was first launched in 2010 and is currently led by Paula Williamson. [12]
Meanwhile, a core outcome measure set based on PROMS was developed with routine data and validated for operationalizing success in multimodal pain therapy. [30] Validation studies suggest also suitability for depicting long-term success in the sense of sustainability of treatment effects.
Improper reporting of health related outcomes: Many hospitals/healthcare providers do not properly report outcomes creating bias in studies. Lack of interpretability of measures/incorporation into clinical practice: Clinicians must be educated about the usefulness of outcome measures, and outcome measures must be easy to include into daily ...
CORE-OM [1] [2] (Clinical Outcomes in Routine Evaluation-Outcome Measure) [3] is a common self-report measure of global distress. It can be used as an initial screening tool and as an assessment tool of the response to psychological therapy .