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The pelvic splanchnic nerves contribute to the innervation of the pelvic and genital organs. [2] The nerves regulate the emptying of the urinary bladder, control opening and closing of the internal urethral sphincter, influence motility in the rectum as well as sexual functions like erection.
Neurogenic bladder dysfunction, often called by the shortened term neurogenic bladder, refers to urinary bladder problems due to disease or injury of the central nervous system or peripheral nerves involved in the control of urination. [1] [2] There are multiple types of neurogenic bladder depending on the underlying cause and the symptoms.
Three spinal nerves in the sacrum (S2–4), commonly referred to as the pelvic splanchnic nerves, also act as parasympathetic nerves. Owing to its location, the parasympathetic system is commonly referred to as having "craniosacral outflow", which stands in contrast to the sympathetic nervous system, which is said to have "thoracolumbar outflow".
While spinal cord injury is a broad and widely-encompassing term, root stimulators may be used for many instances of SCIs. [3] For example, certain cases of spinal cord injuries may sever key nerves necessary to maintain bladder and bowel control. The severance is often the cause of Neurogenic Bowel Dysfunction. [9]
A spinal nerve is a mixed nerve, which carries motor, sensory, and autonomic signals between the spinal cord and the body. In the human body there are 31 pairs of spinal nerves, one on each side of the vertebral column. [1] [2] These are grouped into the corresponding cervical, thoracic, lumbar, sacral and coccygeal regions of the spine. [1]
The pudendal nerve that extends from Onuf's nucleus, connects directly to the rhabdosphincter muscle to control micturation. The sympathetic storage reflex or pelvic-to-hypo-gastric reflex is initiated when the bladder swells. Stretch receptors cause postganglionic neurons to release norepinephrine (NE).
The cauda equina (from Latin tail of horse) is a bundle of spinal nerves and spinal nerve rootlets, consisting of the second through fifth lumbar nerve pairs, the first through fifth sacral nerve pairs, and the coccygeal nerve, all of which arise from the lumbar enlargement and the conus medullaris of the spinal cord.
Cauda equina syndrome (CES) is a condition that occurs when the bundle of nerves below the end of the spinal cord known as the cauda equina is damaged. [2] Signs and symptoms include low back pain, pain that radiates down the leg, numbness around the anus, and loss of bowel or bladder control. [1]