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When combined with inhaled steroids, β adrenoceptor agonists can improve symptoms. [1] [2] In children this benefit is uncertain and they may be potentially harmful. [2]They should not be used without an accompanying steroid due to an increased risk of severe symptoms, including exacerbation in both children and adults. [3]
Levosalbutamol's bronchodilator properties give it indications in treatment of COPD (chronic obstructive pulmonary disease, also known as chronic obstructive lung disease) and asthma. Like other bronchodilators, it acts by relaxing smooth muscle in the bronchial tubes , and thus shortening or reversing an acute "attack" of shortness of breath ...
Clenbuterol is approved for use in some countries as a bronchodilator for asthma. [medical citation needed]Clenbuterol is a β 2 agonist with some structural and pharmacological similarities to epinephrine and salbutamol, but its effects are more potent and longer-lasting as a stimulant and thermogenic drug.
Aclidinium bromide is a long-acting, inhaled muscarinic antagonist (LAMA) approved in the United States in July 2012 [3] as a maintenance treatment for chronic obstructive pulmonary disease (COPD). [4] Evidence shows that it can improve quality of life and prevent hospitalization in those with COPD. [5]
Pulmonary drug delivery is mainly utilized for topical applications in the lungs, such as the use of inhaled beta-agonists, corticosteroids and anticholinergic agents for the treatment of asthma and COPD, the use of inhaled mucolytics and antibiotics for the treatment of cystic fibrosis (CT) and respiratory viral infections, [1] and the use of inhaled prostacyclin analogs for the treatment of ...
Tiotropium is used as maintenance treatment of chronic obstructive pulmonary disease (COPD). [16] [17] It may also be used as an add-on therapy in people with moderate-to-severe asthma on medium to high dose inhaled corticosteroids (ICS). [18] [19] It is not however approved for acute exacerbations of COPD or acute worsening of asthma. [10]
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