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Lenalidomide, sold under the brand name Revlimid among others, is a medication used to treat multiple myeloma, smoldering myeloma, and myelodysplastic syndromes (MDS). [8] For multiple myeloma, it is a first line treatment, and is given with dexamethasone . [ 8 ]
The My Pregnancy app was joined by a My Baby Today app in October 2011. [16] In 2015, BabyCenter released Mom Feed, its first mobile app for parents of toddlers and older children (ages 1 to 8). Mom Feed offered personalized, stage-based information as well as content from the BabyCenter Community and Blog in a real-time stream. [17] [18] [19] [20]
The thalidomide molecule is a synthetic derivative of glutamic acid and consists of a glutarimide ring and a phthaloyl ring (Figure 5). [15] [16] Its IUPAC name is 2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione and it has one chiral center [15] After thalidomide's selective inhibition of TNF-α had been reported, a renewed effort was put in thalidomide's clinical development.
Distribution of gestational age at childbirth among singleton live births, given both when gestational age is estimated by first trimester ultrasound and directly by last menstrual period. About 80% of childbirths occur between 37 and 41 weeks of gestational age, with a somewhat more narrow span when based on first trimester ultrasound.
When it comes to drug pricing, European regulators are a tough sell. Just ask Johnson & Johnson . The U.K.'s National Institute for Health and Care Excellence, or NICE, took a pass on paying for ...
In 2016, MDCalc launched an iOS app, [7] followed by an Android app in 2017. [8] A 2017 survey estimated 65% of U.S. attending physicians and 79% of U.S. resident physicians use MDCalc regularly. [ 1 ]
Thalidomide is a known human teratogen and carries an extremely high risk of severe, life-threatening birth defects if administered or taken during pregnancy. [6] It causes skeletal deformities such as amelia (absence of legs and/or arms), absence of bones, and phocomelia (malformation of the limbs).
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