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A 500 mg laetrile tablet may contain between 2.5 and 25 mg of hydrogen cyanide. [16] Like amygdalin, laetrile is hydrolyzed in the duodenum (alkaline) and in the intestine (enzymatically) to D-glucuronic acid and L-mandelonitrile; the latter hydrolyzes to benzaldehyde and hydrogen cyanide, that in sufficient quantities causes cyanide poisoning ...
They contain amygdalin, which is also known as laetrile. Amygdalin is made up of three components: glucose, benzaldehyde, and cyanide. The amygdalin found in apricot seeds has been marketed as an alternative cancer treatment ; however, studies have shown it to be ineffective in treating cancer. [ 3 ]
Ernst Theodore Krebs Jr. (May 17, 1911 – September 8, 1996) was an American promoter of various substances as alternative cures for cancer, including pangamic acid and amygdalin. He also co-patented the semi-synthetic chemical compound closely related to amygdalin called laetrile, which was
It can be used at a dosage of up to 500 mg four times per day (2,000 mg/day). [ 1 ] [ 8 ] It is used as an aromatase inhibitor to inhibit peripheral estrogen production by mouth at a dosage of 125 mg twice per day (250 mg/day total), without significant suppression of adrenal steroidogenesis at this dosage. [ 17 ]
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Since the 1960s, Oasis of Hope has treated its patients with amygdalin, also known as laetrile, an ineffective and dangerously toxic substance. [6] By 1978, more than 70,000 people in the United States had reportedly been treated with Laetrile. [7]
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Ernesto Contreras (1915–2003) served as a Mexican medical doctor. He operated the Oasis of Hope Hospital in Tijuana for over 30 years, claiming to "treat" cancer patients with amygdalin (also called "laetrile" or, erroneously, "vitamin B 17") which has been found completely ineffective.