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  2. LDL receptor - Wikipedia

    en.wikipedia.org/wiki/LDL_receptor

    The low-density lipoprotein receptor (LDL-R) is a mosaic protein of 839 amino acids (after removal of 21-amino acid signal peptide) [5] that mediates the endocytosis of cholesterol-rich low-density lipoprotein (LDL).

  3. Lambert–Eaton myasthenic syndrome - Wikipedia

    en.wikipedia.org/wiki/Lambert–Eaton_myasthenic...

    The antibodies found in LEMS associated with lung cancer also bind to calcium channels in the cancer cells, and it is presumed that the antibodies originally develop as a reaction to these cells. [4] It has been suggested that the immune reaction to the cancer cells suppresses their growth and improves the prognosis from the cancer. [3] [6]

  4. Signs and symptoms of cancer - Wikipedia

    en.wikipedia.org/wiki/Signs_and_symptoms_of_cancer

    Because many symptoms of cancer are gradual in onset and general in nature, cancer screening (also called cancer surveillance) is a key public health priority. This may include laboratory work, physical examinations, tissue samples, or diagnostic imaging tests that a community of experts recommends be conducted at set intervals for particular ...

  5. LRP1 - Wikipedia

    en.wikipedia.org/wiki/LRP1

    [8] [10] [11] As a member of the LDLR family, LRP1 contains cysteine-rich complement-type repeats, EGF (gene) repeats, β-propeller domains, a transmembrane domain, and a cytoplasmic domain. [9] The extracellular domain of LRP1 is the alpha-chain, which comprises four ligand -binding domains (numbered I-IV) containing two, eight, ten, and ...

  6. Autoimmune autonomic ganglionopathy - Wikipedia

    en.wikipedia.org/wiki/Autoimmune_autonomic...

    When a patient has subacute, severe symptoms or has cancer risk factors, screening computed tomography of the chest is indicated. Some individuals with paraneoplastic autonomic neuropathy have ganglionic AChR antibodies, therefore occult small cell carcinoma or thymoma should be explored.

  7. AL amyloidosis - Wikipedia

    en.wikipedia.org/wiki/AL_amyloidosis

    AL amyloidosis is caused by the deposition of abnormal antibody free light chains. The abnormal light chains are produced by monoclonal plasma cells, and, although AL amyloidosis can occur without diagnosis of another disorder, it is often associated with other plasma cell disorders, such as multiple myeloma and Waldenström's macroglobulinemia. [6]

  8. Gay couple who showed off picture-perfect family get 100 ...

    www.aol.com/news/gay-couple-showed-off-picture...

    A gay Georgia couple convicted of sickening sexually abuse of their two adopted sons will spend the rest of the lives behind bars.. William and Zachary Zulock, 34 and 36, were each sentenced last ...

  9. Acute lymphoblastic leukemia - Wikipedia

    en.wikipedia.org/wiki/Acute_lymphoblastic_leukemia

    Acute lymphoblastic leukemia (ALL) is a cancer of the lymphoid line of blood cells characterized by the development of large numbers of immature lymphocytes. [1] Symptoms may include feeling tired, pale skin color, fever, easy bleeding or bruising, enlarged lymph nodes, or bone pain. [1]

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