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The use of gene therapy is a potential treatment for chronic neuropathic pain. [54] In animals a gene therapy for local transgenes encoding for GABA synthesizing-releasing inhibitory machinery has been demonstrated and was effective for months at a time. It increases synaptically GABA-mediated neuronal inhibition in the spinal cord (or in the ...
Cerebellar ataxia with neuropathy and vestibular areflexia syndrome (CANVAS) is an autosomal recessive late-onset heredodegenerative multisystem neurological disease. The symptoms include poor balance and difficulty walking. Chronic cough and difficulty swallowing may also be present.
Peripheral neuropathy may be classified according to the number and distribution of nerves affected (mononeuropathy, mononeuritis multiplex, or polyneuropathy), the type of nerve fiber predominantly affected (motor, sensory, autonomic), or the process affecting the nerves; e.g., inflammation (), compression (compression neuropathy), chemotherapy (chemotherapy-induced peripheral neuropathy).
Nerve compression syndrome, or compression neuropathy, or nerve entrapment syndrome, is a medical condition caused by chronic, direct pressure on a peripheral nerve. [1] It is known colloquially as a trapped nerve , though this may also refer to nerve root compression (by a herniated disc , for example).
Nerve gliding physical therapy is beneficial in reducing pain intensity, bringing short-term improvements. [8] This treatment was found to manage neural tissue through specific postures and movements of the parts in pain.
MENS uses include treatments for pain, [1] diabetic neuropathy, [2] age-related macular degeneration, wound healing, tendon repair, plantar fasciitis [3] and ruptured ligament recovery. Most microcurrent treatments concentrate on pain and/or speeding healing and recovery. [4]
Diabetic peripheral neuropathy can be diagnosed with a history and physical examination. The diagnosis is considered in people who develop pain or numbness in a leg or foot with a history of diabetes. Muscle weakness, pain, balance loss, and lower limb dysfunction are the most common clinical manifestations. [7]
The Journal of Neurologic Physical Therapy is a monthly peer-reviewed medical journal covering research on physical therapy.It is published by Lippincott Williams & Wilkins and is the official journal of the Neurology Section of the American Physical Therapy Association and the Associação Brasileira de Fisiotherapia Neurofunctional.
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