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Patients with secondary Raynaud's can also have symptoms related to their underlying diseases. Raynaud's phenomenon is the initial symptom that presents for 70% of patients with scleroderma, a skin and joint disease. [citation needed] When Raynaud's phenomenon is limited to one hand or one foot, it is referred to as unilateral Raynaud's.
Lasmiditan is a serotonin receptor agonist that, like the unsuccessful LY-334,370, selectively binds to the 5-HT 1F receptor subtype. A number of triptans have been shown to act on this subtype as well, but only after their affinity for 5-HT 1B and 5-HT 1D has been made responsible for their anti-migraine activity.
In extreme cases, the affected person may lose fingers. The effects are cumulative. When symptoms first appear, they may disappear after a short time. If exposure to vibration continues over months or years, the symptoms can worsen and become permanent. [4] Exposure to hand arm vibrations is a respectively newer occupational hazard in the work ...
No cure for scleroderma is known, although relief of symptoms is often achieved; these include treatment of: [13] [31] Raynaud's phenomenon with vasodilators such as calcium channel blockers, alpha blockers, serotonin receptor antagonists, angiotensin II receptor inhibitors, statins, local nitrates or iloprost
The most prevalent skin change is Raynaud's phenomenon, which usually appears early in the course of the disease. [14] Swollen digits are a common sign, and on occasion, the complete hand swells. [15] [16] Acrosclerosis, also known as sclerodactyly, can develop with or without proximal scleroderma and is usually a later symptom of the condition ...
The term Raynaud's does this and is the term used by the NIH. This ref specifically says "People who have primary Raynaud's (Raynaud's disease) or secondary Raynaud's (Raynaud's phenomenon)" Doc James (talk · contribs · email) 17:36, 1 October 2016 (UTC) Support this is the ICD10 preferred name. We and all medical naming conventions are ...
Moxisylyte, also known as thymoxamine, is a drug used in urology for the treatment of erectile dysfunction. [1] It is an α 1-adrenergic antagonist. [2] In the United Kingdom, Moxisylte is marketed as Opilon (Archimedes Pharma UK Ltd) and is used for the short-term treatment of primary Raynaud's syndrome.
A case series in 2010 found that peripheral vascular symptoms, such as cold hands and feet (e.g., Raynaud syndrome), were more common in people with IH than in controls. [ 17 ] Other autonomic dysfunctional symptoms, such as fainting episodes , dizziness upon arising , possibly migrainous headaches, food cravings, and impotence may also be ...