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One can distinguish between "recipes" originating in traditional folk medicine [2] and those of which the author is known. When scientifically analyzed, the "gallstones" produced by a group of patients were found to contain no cholesterol, bilirubin, or calcium, which characterizes the makeup of gallstones, but instead were 75% fatty acids. [1]
As diarrhea is frequent when CDCA is used in gallstone dissolution, it has been studied as a possible treatment for constipation and has been shown to accelerate colonic transit and improve bowel function. [11] The Australian biotechnology company Giaconda has tested a treatment for hepatitis C infection that combines chenodeoxycholic acid with ...
Ozempic has fast become a household name. In addition to helping people with diabetes manage their blood sugar levels, this GLP-1 (glucagon-like peptide 1 receptor agonist) medication helps reduce ...
Gallstones may result from increased saturation of cholesterol or bilirubin, or from bile stasis. Lower concentrations of bile acids or phospholipids in bile reduce cholesterol solubility and lead to microcrystal formation. Oral therapy with chenodeoxycholic acid and/or ursodeoxycholic acid has been used to dissolve cholesterol gallstones.
The medications ursodeoxycholic acid (UDCA) and chenodeoxycholic acid (CDCA) have been used in treatment to dissolve gallstones. [58] [59] A 2013 meta-analysis concluded that UDCA or higher dietary fat content appeared to prevent formation of gallstones during weight loss. [41]
However, VLCD may increase the risk of developing gallstones if the fat content of VLCD is not sufficient, but data is lacking to know the precise amount of fat that is necessary to avoid gallstones formation. [26] [27] Indeed, dietary fat stimulates gall bladder contraction, thus, if following a fat-free VLCD, the bladder does not empty. [26]
Switching from a diet with protein provided by casein to a diet with protein provided by salmon protein hydrolysate led to as much as a 6-fold increase in levels of bile acids in the blood plasma of rats. [45] In humans, adding high protein to a high fat diet raised the level of deoxycholate in the plasma by almost 50%. [46]
The usual treatment for gallstones is surgical removal of the gallbladder - cholecystectomy. Laparoscopic cholecystectomy is a routine operation nowadays. Note: Unsure if I can use any of this as possible information in the Gallstone entry but it is information I found lacking during my ordeal when i was searching for answers, that I now have a ...