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2-Bromopyridine reacts with butyllithium to give 2-lithiopyridine, [2] which is a versatile reagent. [3] Pyrithione can be prepared in a two-step synthesis from 2-bromopyridine by oxidation to the N-oxide with a suitable peracid followed by substitution using either sodium dithionite or sodium sulfide with sodium hydroxide to introduce the thiol functional group.
2-Aminopyridine is an organic compound with the formula H 2 NC 5 H 4 N. It is one of three isomeric aminopyridines. It is a colourless solid that is used in the production of the drugs piroxicam, sulfapyridine, tenoxicam, and tripelennamine. It is produced by the reaction of sodium amide with pyridine, the Chichibabin reaction. [3]
[4] [5] Bromazolam is a non subtype selective agonist at the benzodiazepine site of GABA A receptors, with a binding affinity of 2.81 nM at the α 1 subtype, 0.69 nM at α 2 and 0.62 nM at α 5. [6] The "common" dosage range for users of bromazolam was reported to be 1–2 mg, suggesting its potency is similar to alprazolam.
The reaction of 3-bromo-4-chloropyridine with furan and lithium amalgam gives 1,4-epoxy-dihydroquinoline through the 2,3-pyridyne intermediate. The reaction of 4-bromopyridine with sodium in liquid ammonia gives both 3-aminopyridine and 4-aminopyridine through the 3,4-pyridyne intermediate and an E1cB-elimination reaction .
3-Bromopyridine is an aryl bromide and isomer of bromopyridine with the formula C 5 H 4 BrN. It is a colorless liquid that is mainly used as a building block in organic synthesis. [1] [2] It participates as a substrate in many reactions associated with aryl halides, e.g., the Heck reaction [3] and Buchwald-Hartwig coupling. [4]
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2-pyridinecarboxylic acid 3-pyridinecarboxylic acid 4-pyridinecarboxylic acid Structural Formula: CAS Registry Number: 98-98-6 59-67-6 55-22-1
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