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  2. Bromotoluene - Wikipedia

    en.wikipedia.org/wiki/Bromotoluene

    Monobromotoluene isomers [1] [2] [3] Common name Structure Systematic name: 1-bromo-2-methylbenzene 1-bromo-3-methylbenzene 1-bromo-4-methylbenzene Molecular formula: C 7 H 7 Br (C 6 H 4 BrCH 3) Molar mass: 171.03 g/mol Appearance colorless liquid colorless liquid white crystalline solid CAS number [95-46-5] [591-17-3]

  3. 4-Nitrotoluene - Wikipedia

    en.wikipedia.org/wiki/4-Nitrotoluene

    4-Nitrotoluene or para-nitrotoluene is an organic compound with the formula CH 3 C 6 H 4 NO 2. It is a pale yellow solid. It is a pale yellow solid. It is one of three isomers of nitrotoluene .

  4. Bartoli indole synthesis - Wikipedia

    en.wikipedia.org/wiki/Bartoli_indole_synthesis

    The reaction mechanism [8] of the Bartoli indole synthesis is illustrated below using o-nitrotoluene (1) and propenyl Grignard (2) to form 3,7-dimethylindole (13). The mechanism of the Bartoli indole synthesis. The mechanism begins by the addition of the Grignard reagent (2) onto the nitroarene (1) to form intermediate 3.

  5. o-Toluidine - Wikipedia

    en.wikipedia.org/wiki/O-Toluidine

    o-Toluidine is absorbed through inhalation and dermal contact as well as from the gastrointestinal tract. [19] [13] [20] [21]The metabolism of o-toluidine involves many competing activating and deactivating pathways, including N-acetylation, N-oxidation, and N-hydroxylation, and ring oxidation.

  6. Étard reaction - Wikipedia

    en.wikipedia.org/wiki/Étard_reaction

    For example, the first step in the synthesis of ephedrine is condensation of benzaldehyde with nitroethane [citation needed]. Additionally, benzaldehyde is instrumental in the synthesis of phentermine. [10] Unlike other oxidising agents (like KMnO 4 or CrO 3 etc.), chromyl chloride does not oxidise aldehyde to carboxylic acid.

  7. Béchamp reduction - Wikipedia

    en.wikipedia.org/wiki/Béchamp_reduction

    4 c 6 h 5 no 2 + 9 fe + 4 h 2 o → 4 c 6 h 5 nh 2 + 3 fe 3 o 4 This reaction was once a major route to aniline, but catalytic hydrogenation is the preferred method. [ 2 ]

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  9. N-Bromosuccinimide - Wikipedia

    en.wikipedia.org/wiki/N-Bromosuccinimide

    NBS will react with alkenes 1 in aqueous solvents to give bromohydrins 2. The preferred conditions are the portionwise addition of NBS to a solution of the alkene in 50% aqueous DMSO, DME, THF, or tert-butanol at 0 °C. [3] Formation of a bromonium ion and immediate attack by water gives strong Markovnikov addition and anti stereochemical ...