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In humans, the DMD gene is located on the short (p) arm of the X chromosome between positions 21.2 and 21.1. Dystrophin is a rod-shaped cytoplasmic protein, and a vital part of a protein complex that connects the cytoskeleton of a muscle fiber to the surrounding extracellular matrix through the cell membrane.
Human karyogram. Neurogenetics studies the role of genetics in the development and function of the nervous system.It considers neural characteristics as phenotypes (i.e. manifestations, measurable or not, of the genetic make-up of an individual), and is mainly based on the observation that the nervous systems of individuals, even of those belonging to the same species, may not be identical.
Variations in the sequence of titin between different types of striated muscle (cardiac or skeletal) have been correlated with differences in the mechanical properties of these muscles. [ 6 ] [ 12 ] Titin is the third most abundant protein in muscle (after myosin and actin ), and an adult human contains approximately 0.5 kg of titin. [ 13 ]
Muscle tissue contains special contractile proteins called actin and myosin which interact to cause movement. Among many other muscle proteins, present are two regulatory proteins, troponin and tropomyosin. [1] Muscle tissue varies with function and location in the body. In vertebrates, the three types are: skeletal, cardiac (both striated), and
There are four basic types of animal tissues: muscle tissue, nervous tissue, connective tissue, and epithelial tissue. [5] [9] All animal tissues are considered to be subtypes of these four principal tissue types (for example, blood is classified as connective tissue, since the blood cells are suspended in an extracellular matrix, the plasma). [9]
Muscle cells (myocytes) form the active contractile tissue of the body. Muscle tissue functions to produce force and cause motion, either locomotion or movement within internal organs. Muscle is formed of contractile filaments and is separated into three main types; smooth muscle, skeletal muscle and cardiac muscle.
The majority of this type of muscle tissue is found in the digestive and urinary systems where it acts by propelling forward food, chyme, and feces in the former and urine in the latter. Other places smooth muscle can be found are within the uterus, where it helps facilitate birth, and the eye, where the pupillary sphincter controls pupil size. [3]
The number of muscle fibers within each unit can vary within a particular muscle and even more from muscle to muscle: the muscles that act on the largest body masses have motor units that contain more muscle fibers, whereas smaller muscles contain fewer muscle fibers in each motor unit. [1] For instance, thigh muscles can have a thousand fibers ...