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  2. Resolution (chromatography) - Wikipedia

    en.wikipedia.org/wiki/Resolution_(chromatography)

    Example chromatogram showing signal as a function of retention time. In chromatography, resolution is a measure of the separation of two peaks of different retention time t in a chromatogram. [1] [2] [3] [4]

  3. Fundamental resolution equation - Wikipedia

    en.wikipedia.org/wiki/Fundamental_Resolution...

    So what does this mean? It means that to increase resolution of two peaks on a chromatogram, one of the three terms of the equation need to be modified. 1) N can be increased by lengthening the column (least effective, as doubling the column will get a 2 1/2 or 1.44x increase in resolution). 2) Increasing k' also helps.

  4. Chromatography - Wikipedia

    en.wikipedia.org/wiki/Chromatography

    Analytical chromatography – the use of chromatography to determine the existence and possibly also the concentration of analyte(s) in a sample. Bonded phase – a stationary phase that is covalently bonded to the support particles or to the inside wall of the column tubing.

  5. Column chromatography - Wikipedia

    en.wikipedia.org/wiki/Column_chromatography

    Column chromatography in chemistry is a ... This data is a good way of determining the column's separation properties of that particular sample. The resolution can be ...

  6. Reversed-phase chromatography - Wikipedia

    en.wikipedia.org/wiki/Reversed-phase_chromatography

    Reversed-phase liquid chromatography (RP-LC) is a mode of liquid chromatography in which non-polar stationary phase and polar mobile phases are used for the separation of organic compounds. [ 1 ] [ 2 ] [ 3 ] The vast majority of separations and analyses using high-performance liquid chromatography (HPLC) in recent years are done using the ...

  7. Unresolved complex mixture - Wikipedia

    en.wikipedia.org/wiki/Unresolved_Complex_Mixture

    A relatively recent analytical tool that has been used for the separation of UCMs is comprehensive two-dimensional GC ().This powerful technique, introduced by Liu and Phillips [20] combines two GC columns with different separation mechanisms: typically a primary column that separates compounds based on volatility coupled to a second short column that separates by polarity.

  8. Purnell equation - Wikipedia

    en.wikipedia.org/wiki/Purnell_equation

    The Purnell equation is an equation used in analytical chemistry to calculate the resolution R s between two peaks in a chromatogram. [1] [2]= (′ + ′) where R s is the resolution between the two peaks

  9. Kinetic resolution - Wikipedia

    en.wikipedia.org/wiki/Kinetic_resolution

    In organic chemistry, kinetic resolution is a means of differentiating two enantiomers in a racemic mixture. In kinetic resolution, two enantiomers react with different reaction rates in a chemical reaction with a chiral catalyst or reagent, resulting in an enantioenriched sample of the less reactive enantiomer. [ 1 ]