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Auto-brewery syndrome (ABS) (also known as gut fermentation syndrome, endogenous ethanol fermentation or drunkenness disease) is a condition characterized by the fermentation of ingested carbohydrates in the gastrointestinal tract of the body caused by bacteria or fungi. [1]
[4] [6] Alcohol dehydrogenase and aldehyde dehydrogenase are present at their highest concentrations (in liver mitochondria). [98] [107] But these enzymes are widely expressed throughout the body, such as in the stomach and small intestine. [2] Some alcohol undergoes a first pass of metabolism in these areas, before it ever enters the ...
Alcohol flush reaction is a condition in which an individual's face or body experiences flushes (appears red) or blotches as a result of an accumulation of acetaldehyde, a metabolic byproduct of the catabolic metabolism of alcohol. It is best known as a condition that is experienced by people of Asian descent.
Basically, the gut microbiome begins fermenting carbohydrates and sugars into alcohol. When it gets to the blood, it can be detected like it would if someone had been drinking. “There are ...
When you overindulge in alcohol, your liver, which is responsible for breaking down toxins like alcohol, can become overworked, explains Andrews. This may lead to fat buildup, inflammation and ...
In contrast, alcohol allergy involves the immune system mistakenly identifying alcohol or its components, such as sulfites (preservatives commonly used in alcoholic beverages to prevent spoilage) and histamines (chemical compounds naturally produced during fermentation that can trigger inflammatory responses), as harmful, thereby triggering an ...
Alcohol is classified as carcinogenic to humans by the International Agency for Research on Cancer. “Excessive or long-term consumption of alcohol has been linked to an increased risk of various ...
In addition to respiratory failure and accidents caused by its effects on the central nervous system, alcohol causes significant metabolic derangements. Hypoglycaemia occurs due to ethanol's inhibition of gluconeogenesis , especially in children, and may cause lactic acidosis , ketoacidosis , and acute kidney injury .