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Grape seed extract is sold as a dietary supplement. [6] The US National Center for Complementary and Integrative Health reported that oral administration of grape seed extract (dose and frequency unreported) was well tolerated in people over 14 weeks. [1] Side effects may include itchy scalp, dizziness, headache, and nausea. [1]
Proanthocyanidins are a class of polyphenols found in many plants, such as cranberry, blueberry, and grape seeds. Chemically, they are oligomeric flavonoids. Many are oligomers of catechin and epicatechin and their gallic acid esters. More complex polyphenols, having the same polymeric building block, form the group of condensed tannins.
Resveratrol (3,5,4′-trihydroxy-trans-stilbene) is a stilbenoid, a type of natural phenol or polyphenol and a phytoalexin produced by several plants in response to injury or when the plant is under attack by pathogens, such as bacteria or fungi.
Procyanidin content in dietary supplements has not been well documented. [26] Pycnogenol is a dietary supplement derived from extracts from maritime pine bark that contains 70% procyanidins, and is marketed with claims it can treat many conditions.
Naringenin is a flavanone from the flavonoid group of polyphenols. [2] It is commonly found in citrus fruits, especially as the predominant flavonone in grapefruit. [2]The fate and biological functions of naringenin in vivo are unknown, remaining under preliminary research, as of 2024. [2]
Apples are a major source of fiber, and contain vitamin C and polyphenols, a type of phytochemical with a cholesterol-lowering effect, the Nutrients study notes. ... Daily grape intake can ...
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