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  2. Reactive lymphocyte - Wikipedia

    en.wikipedia.org/wiki/Reactive_lymphocyte

    Reactive lymphocyte surrounded by red blood cells. In immunology, reactive lymphocytes, variant lymphocytes, atypical lymphocytes, Downey cells or Türk cells are cytotoxic (CD8 +) lymphocytes that become large as a result of antigen stimulation. Typically, they can be more than 30 μm in diameter with varying size and shape.

  3. Lymphoproliferative disorders - Wikipedia

    en.wikipedia.org/wiki/Lymphoproliferative_disorders

    Children with common variable immunodeficiency (CVID) are also at a higher risk of developing a lymphoproliferative disorder. [ citation needed ] Some disorders that predispose a person to lymphoproliferative disorders are severe combined immunodeficiency (SCID), Chédiak–Higashi syndrome , Wiskott–Aldrich syndrome (an X-linked recessive ...

  4. Epstein–Barr virus–associated lymphoproliferative diseases (also abbreviated EBV-associated lymphoproliferative diseases or EBV+ LPD) are a group of disorders in which one or more types of lymphoid cells (a type of white blood cell), i.e. B cells, T cells, NK cells, and histiocytic-dendritic cells, are infected with the Epstein–Barr virus (EBV).

  5. Hemophagocytic lymphohistiocytosis - Wikipedia

    en.wikipedia.org/wiki/Hemophagocytic_lymphohist...

    It is a life-threatening disease of severe hyperinflammation caused by uncontrolled proliferation of benign lymphocytes and macrophages that secrete high amounts of inflammatory cytokines. It is classified as one of the cytokine storm syndromes. There are inherited and non-inherited (acquired) causes of HLH.

  6. Drug rash with eosinophilia and systemic symptoms - Wikipedia

    en.wikipedia.org/wiki/Drug_rash_with_eosinophil...

    The symptoms of DRESS syndrome usually begin 2 to 6 weeks but uncommonly up to 8–16 weeks after exposure to an offending drug. Symptoms generally include fever, an often itchy rash which may be morbilliform or consist mainly of macules or plaques, facial edema (i.e. swelling, which is a hallmark of the disease), enlarged and sometimes painful lymph nodes, and other symptoms due to ...

  7. Autoimmune lymphoproliferative syndrome - Wikipedia

    en.wikipedia.org/wiki/Autoimmune_lymphoprolife...

    It affects lymphocyte apoptosis. [2] It is a rare genetic disorder of abnormal lymphocyte survival caused by defective Fas mediated apoptosis. [3] Normally, after infectious insult, the immune system down-regulates by increasing Fas expression on activated B and T lymphocytes and Fas-ligand on activated T lymphocytes.

  8. Lymphomatoid papulosis - Wikipedia

    en.wikipedia.org/wiki/Lymphomatoid_papulosis

    Wedge-shaped clusters of large atypical lymphocytes that are CD30+, interspersed with a mixed inflammatory infiltrate of neutrophils, histiocytes, and eosinophils. B Similar to mycosis fungoides , with bandlike infiltrate and epidermotropism of smaller atypical lymphocytes that may be CD30-.

  9. Sézary disease - Wikipedia

    en.wikipedia.org/wiki/Sézary_disease

    The disease's origin is a peripheral CD4+ T-lymphocyte, [3] although rarer CD8+/CD4- cases have been observed. [3] Epidermotropism (lymphocytes residing in the epidermis) [6] by neoplastic CD4+ lymphocytes with the formation of Pautrier's microabscesses is the hallmark sign of the disease. Although the condition can affect people of all ages ...

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