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Low intensity pulsed ultrasound has been proposed as a therapy to support bone healing after fractures, [1] osteomies, or delayed healing. A 2017 review, however, found no trustworthy evidence for the use of low intensity pulsed ultrasound for bone healing, mostly based on the large pragmatic randomized controlled trial published in 2016.
Marrow-nucleated cells are used every day in regenerative orthopedics. The knee microfracture surgery technique relies on the release of these cells into a cartilage lesion to initiate fibrocartilage repair in osteochondral defects. [13] In addition, this cell population has also been shown to assist in the repair of non-union fractures. [14]
Platelet-rich plasma (PRP) is an emerging technique in tissue regeneration, increasingly used to enhance healing in dental and oral surgery, particularly for aging patients. PRP is derived from the patient's blood through centrifugation , concentrating growth factors that are crucial for wound healing and tissue repair.
Therefore, a brace is often used to immobilize the knee for one to two weeks. Evidence suggests that the hamstring tendon graft does as well, or nearly as well, as the patellar ligament graft in the long term. [10] A Cochrane review in 2011 found insufficient evidence to suggest whether a hamstring versus patellar ligament graft was superior. [11]
The natural movement promoted the alignment of the new fibers and tendocytes with the natural alignment found in uninjured tendons. Stem cell treatment not only allowed more horses to return to full duty and also greatly reduced the re-injury rate over a three-year period. [23] The use of embryonic stem cells has also been applied to tendon repair.
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Research in the NFB focuses on devising new strategies for repair of peripheral nerve injuries using a combination of biomaterials and tissue engineering methodologies. [25] Regeneration of the central nervous system is much poorer than the peripheral nervous system and does not show the same capacity to regenerate itself.
There is no evidence to support the use of ultrasound for the treatment of low back pain, [24] and current clinical guidelines recommend that ultrasound is not used for this condition. [25] In a critical review, it was demonstrated that therapeutic ultrasound was effective in improving pain, function, and cartilage repair in knee osteoarthritis.
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