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Drug precursors, also referred to as precursor chemicals or simply precursors, are substances used to manufacture illicit drugs. Most precursors also have legitimate commercial uses and are legally used in a wide variety of industrial processes and consumer products, such as medicines, flavourings, and fragrances.
Coca-Cola used coca leaf extract in its products from 1885 until about 1903, when it began using decocainized leaf extract. [9] [10] [11] Extraction of cocaine from coca requires several solvents and a chemical process known as an acid–base extraction, which can fairly easily extract the alkaloids from the plant.
The highest prevalence of cocaine use was in Australia and New Zealand (2.1%), followed by North America (2.1%), Western and Central Europe (1.4%), and South and Central America (1.0%). [36] Since 1961, the Single Convention on Narcotic Drugs has required countries to make recreational use of cocaine a crime. [37]
All listed chemicals [5] as specified in 21 CFR 1310.02 (a) or (b). This includes supplements which contain a listed chemical, regardless of their dosage form or packaging and regardless of whether the chemical mixture, drug product or dietary supplement is exempt from regulatory controls. For each chemical, its illicit manufacturing use is ...
Black cocaine, and cocaine paste, are impure forms of cocaine. The most common cocaine adulterants found in 1998 in samples in Rome , Italy were lidocaine and caffeine . [ 20 ] Cocaine is sometimes mixed with methylamphetamine , methylphenidate , and ephedrine , but is usually mixed with non psychoactive chemicals such as mannitol , inositol ...
The hepatic enzyme carboxylesterase is an important part of cocaine's metabolism because it acts as a catalyst for the hydrolysis of cocaine in the liver, which produces these inactive metabolites. If ethanol is present during the metabolism of cocaine, a portion of the cocaine undergoes transesterification with ethanol, rather than undergoing ...
In South America, coca paste, also known as cocaine base and, therefore, often confused with cocaine sulfate in North America, is relatively inexpensive and is widely used by low-income populations. The coca paste is smoked in tobacco or cannabis cigarettes and use has become widespread in several Latin American countries.
Hindu religion in India, Rastafari movements, Cannabis-based religions like First Church of Cannabis or International Church of Cannabis and other various groups (see entheogenic use of cannabis) Chacruna: Psychotria viridis: Leaf: DMT Psychedelic: UDV of Peru, Ecuador, Colombia, and the Brazilian church. Santo Daime have used it as part of ...