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  2. Typical antipsychotic - Wikipedia

    en.wikipedia.org/wiki/Typical_antipsychotic

    Typical antipsychotics (also known as major tranquilizers, and first generation antipsychotics) are a class of antipsychotic drugs first developed in the 1950s and used to treat psychosis (in particular, schizophrenia). Typical antipsychotics may also be used for the treatment of acute mania, agitation, and other conditions.

  3. Antipsychotic - Wikipedia

    en.wikipedia.org/wiki/Antipsychotic

    Placebo-controlled trials of both first- and second-generation antipsychotic drugs consistently demonstrate the superiority of active drugs over placebos in suppressing psychotic symptoms. [25] A large meta-analysis of 38 trials of antipsychotic drugs in schizophrenia with acute psychotic episodes showed an effect size of about 0.5. [37]

  4. FDA approves 1st new drug for schizophrenia in more ... - AOL

    www.aol.com/fda-approves-1st-drug-schizophrenia...

    The first drugs for schizophrenia, including chlorpromazine and haloperidol – also known by the brand names Thorazine and Haldol, respectively – were introduced in the 1950s and revolutionized ...

  5. Clozapine - Wikipedia

    en.wikipedia.org/wiki/Clozapine

    Clozapine, sold under the brand name Clozaril among others, is a psychiatric medication and was the first atypical antipsychotic to be discovered. [6] It is primarily used to treat people with schizophrenia and schizoaffective disorder who have had an inadequate response to two other antipsychotics, or who have been unable to tolerate other drugs due to extrapyramidal side effects.

  6. FDA Approves the First New Schizophrenia Drug in Decades - AOL

    www.aol.com/lifestyle/fda-approves-first...

    The medicine works in an entirely different way from existing treatments.

  7. Thioridazine - Wikipedia

    en.wikipedia.org/wiki/Thioridazine

    Thioridazine (Mellaril or Melleril) is a first generation antipsychotic drug belonging to the phenothiazine drug group and was previously widely used in the treatment of schizophrenia and psychosis. The branded product was withdrawn worldwide in 2005 because it caused severe cardiac arrhythmias. However, generic versions are still available in ...

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