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  2. Acromegaly - Wikipedia

    en.wikipedia.org/wiki/Acromegaly

    About 98% of cases of acromegaly are due to the overproduction of growth hormone by a benign tumor of the pituitary gland called an adenoma. [17] These tumors produce excessive growth hormone and compress surrounding brain tissues as they grow larger. In some cases, they may compress the optic nerves. Expansion of the tumor may cause headaches ...

  3. Pituitary adenoma - Wikipedia

    en.wikipedia.org/wiki/Pituitary_adenoma

    Acromegaly is a syndrome that results when the anterior pituitary gland produces excess growth hormone (GH). Approximately 90–95% of acromegaly cases are caused by a pituitary adenoma and it most commonly affects middle aged adults, [18] Acromegly can result in severe disfigurement, serious complicating conditions, and premature death if ...

  4. Hypersomatotropism (veterinary) - Wikipedia

    en.wikipedia.org/wiki/Hypersomatotropism...

    In bitches with spontaneous acromegaly brought on by oestrous, their progesterone levels are normal; however, growth hormone levels are increased. Recovery following an ovariohysterectomy may be possible. The reason as to why some bitches develop acromegaly and diabetes mellitus during the oestrous cycle is unknown. [1]

  5. Hyperpituitarism - Wikipedia

    en.wikipedia.org/wiki/Hyperpituitarism

    Hyperpituitarism is a condition due to the primary hypersecretion of pituitary hormones; [3] [medical citation needed] it typically results from a pituitary adenoma.In children with hyperpituitarism, disruption of growth regulation is rare, either because of hormone hypersecretion or because of manifestations caused by local compression of the adenoma.

  6. Macrocytosis - Wikipedia

    en.wikipedia.org/wiki/Macrocytosis

    Symptoms, Complete blood count, Peripheral blood smear, Vitamin B12 level, Red cell folate level Macrocytosis is a condition where red blood cells are larger than normal. [ 1 ] These enlarged cells, also known as macrocytes, are defined by a mean corpuscular volume (MCV) that exceeds the upper reference range established by the laboratory and ...

  7. Polycythemia - Wikipedia

    en.wikipedia.org/wiki/Polycythemia

    Primary polycythemias are myeloproliferative diseases affecting red blood cell precursors in the bone marrow. Polycythemia vera (PCV) (a.k.a. polycythemia rubra vera (PRV)) occurs when excess red blood cells are produced as a result of an abnormality of the bone marrow. [3] Often, excess white blood cells and platelets are also produced.

  8. Bone marrow - Wikipedia

    en.wikipedia.org/wiki/Bone_marrow

    Bone marrow is a semi-solid tissue found within the spongy (also known as cancellous) portions of bones. [2] In birds and mammals, bone marrow is the primary site of new blood cell production (or haematopoiesis). [3] It is composed of hematopoietic cells, marrow adipose tissue, and supportive stromal cells.

  9. Erythropoietin - Wikipedia

    en.wikipedia.org/wiki/Erythropoietin

    Erythropoietin (/ ɪ ˌ r ɪ θ r oʊ ˈ p ɔɪ. ɪ t ɪ n,-r ə-,-p ɔɪ ˈ ɛ t ɪ n,-ˈ iː t ɪ n /; [1] [2] [3] EPO), also known as erythropoetin, haematopoietin, or haemopoietin, is a glycoprotein cytokine secreted mainly by the kidneys in response to cellular hypoxia; it stimulates red blood cell production (erythropoiesis) in the bone marrow.