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Viagra or sildenafil, the active ingredient and generic version, is a PDE-5 inhibitor that widens blood vessels inside the member to allow better blood flow for stronger or longer-lasting arousal.
Recreational Viagra use does happen, and while some men see harmless benefits from the active ingredient in the famous “little blue pill,” they’re still taking a significant risk every time ...
In 2000, Viagra sales accounted for 92% of the global market for prescribed erectile dysfunction pills. [77] By 2007, Viagra's global share had plunged to about 50% [78] due to several factors, including the entry of Cialis and Levitra, along with several counterfeits and clones, and reports of vision loss in people taking PDE5 inhibitors.
Many of these pills work fairly quickly. Sildenafil (Viagra), tadalafil (Cialis) and vardenafil (Levitra) typically start working within 30 to 60 minutes, while avanafil (Stendra) works within 15 ...
For instance, a pill of ecstasy costs between €0.20 and €0.30 and it is generally sold at €5. A Viagra pill costs around €0.15 and it is sold via an illicit website at around 8 to €10. A kilo of counterfeit Viagra pills (1,700 units) costs €255 and the retail value is from 13,600 to €17,000.
Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.
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