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Testicular cancer, ovarian cancer, lung cancer, acute myeloid leukaemia, lymphomas and sarcomas: Myelosuppression, hypersensitivity reactions, Stevens–Johnson syndrome (rare), peripheral neuropathy (uncommon) and secondary malignancies (especially acute myeloid leukaemia). Teniposide: IV: Topoisomerase II inhibitor.
[25] it started in 2013 a phase III for metastatic germline BRCA mutated breast cancer. [26] Veliparib June 2014 in phase III trials, for advanced ovarian cancer, triple-negative breast cancer and in non-small cell lung cancer (NSCLC). [27] Pamiparib (BGB-290) For ovarian cancer, 1st patient enrolled May 2018. [28] It is a PARP1 and PARP2 ...
ONX-0801 (BGC 945) is an experimental drug that has been developed to target ovarian cancer. [1] It is a folate receptor alpha mediated thymidylate synthase inhibitor. [2] [3] ONX-0801 was originally developed by BTG and the Institute of Cancer Research in the UK, and subsequently licensed to Onyx Pharmaceuticals for clinical
AbbVie will also get access to Immunogen's follow-on pipeline of ADCs, including early-stage ovarian cancer candidate IMGN-151 and a mid-stage drug pivekimab sunirine for a rare type of blood cancer.
(Reuters) -The U.S. Food and Drug Administration said on Friday it had granted traditional approval for AbbVie's "guided missile" cancer therapy, Elahere, for patients with a type of ovarian cancer.
This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs that have been withdrawn from market; consequently, the column Use does not necessarily indicate clinical usage. See the list of FDA-approved therapeutic monoclonal antibodies in the monoclonal antibody therapy page.
recurrent ovarian cancer responsive to platinum-based chemotherapy Ocrelizumab [2] Genentech: multiple sclerosis: Dupilumab [2] Regeneron Pharmaceuticals: atopic dermatitis: Palbociclib [2] Pfizer: HR-positive, HER2-negative breast cancer Valbenazine [2] Neurocrine Biosciences: tardive dyskinesia: Ranibizumab [2] Genentech: diabetic retinopathy ...
Olaparib, sold under the brand name Lynparza, is a medication for the maintenance treatment of BRCA-mutated advanced ovarian cancer in adults.It is a PARP inhibitor, inhibiting poly ADP ribose polymerase (PARP), an enzyme involved in DNA repair.
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