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Testicular cancer, ovarian cancer, lung cancer, acute myeloid leukaemia, lymphomas and sarcomas: Myelosuppression, hypersensitivity reactions, Stevens–Johnson syndrome (rare), peripheral neuropathy (uncommon) and secondary malignancies (especially acute myeloid leukaemia). Teniposide: IV: Topoisomerase II inhibitor.
[25] it started in 2013 a phase III for metastatic germline BRCA mutated breast cancer. [26] Veliparib June 2014 in phase III trials, for advanced ovarian cancer, triple-negative breast cancer and in non-small cell lung cancer (NSCLC). [27] Pamiparib (BGB-290) For ovarian cancer, 1st patient enrolled May 2018. [28] It is a PARP1 and PARP2 ...
ONX-0801 (BGC 945) is an experimental drug that has been developed to target ovarian cancer. [1] It is a folate receptor alpha mediated thymidylate synthase inhibitor. [2] [3] ONX-0801 was originally developed by BTG and the Institute of Cancer Research in the UK, and subsequently licensed to Onyx Pharmaceuticals for clinical
(Reuters) -The U.S. Food and Drug Administration said on Friday it had granted traditional approval for AbbVie's "guided missile" cancer therapy, Elahere, for patients with a type of ovarian cancer.
This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs that have been withdrawn from market; consequently, the column Use does not necessarily indicate clinical usage. See the list of FDA-approved therapeutic monoclonal antibodies in the monoclonal antibody therapy page.
AbbVie will also get access to Immunogen's follow-on pipeline of ADCs, including early-stage ovarian cancer candidate IMGN-151 and a mid-stage drug pivekimab sunirine for a rare type of blood cancer.
recurrent ovarian cancer responsive to platinum-based chemotherapy Ocrelizumab [2] Genentech: multiple sclerosis: Dupilumab [2] Regeneron Pharmaceuticals: atopic dermatitis: Palbociclib [2] Pfizer: HR-positive, HER2-negative breast cancer Valbenazine [2] Neurocrine Biosciences: tardive dyskinesia: Ranibizumab [2] Genentech: diabetic retinopathy ...
Olaparib, sold under the brand name Lynparza, is a medication for the maintenance treatment of BRCA-mutated advanced ovarian cancer in adults.It is a PARP inhibitor, inhibiting poly ADP ribose polymerase (PARP), an enzyme involved in DNA repair.
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