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Diagram showing the reduction in number of the chromosomes in the process of maturation of the ovum; the process is known as meiosis Main article: Oogenesis The formation of an oocyte is called oocytogenesis, which is a part of oogenesis. [ 1 ]
Oogenesis starts with the process of developing primary oocytes, which occurs via the transformation of oogonia into primary [oocyte]s, a process called oocytogenesis. [11] From one single oogonium, only one mature oocyte will rise, with 3 other cells called polar bodies. Oocytogenesis is complete either before or shortly after birth.
Oocytogenesis : third trimester primary Oocyte: diploid/46: 4C: Ootidogenesis (meiosis 1) (Folliculogenesis) -- polar body separated: Dictyate in prophase I until ovulation secondary Oocyte: haploid/23: 2C: Ootidogenesis (meiosis 2) -- polar body separated: Halted in metaphase II until fertilization Ootid: haploid/23: 1C: Maturation: Minutes ...
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As a part of the process of in vitro fertilization, gene expression profiling of cumulus cells can be performed to estimate oocyte quality and the efficiency of an ovarian hyperstimulation protocol, and may indirectly predict oocyte aneuploidy, embryo development and pregnancy outcomes.
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Fertilization was not understood in antiquity. Hippocrates believed that the embryo was the product of male semen and a female factor. But Aristotle held that only male semen gave rise to an embryo, while the female only provided a place for the embryo to develop, [5] a concept he acquired from the preformationist Pythagoras.
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