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  2. Lenalidomide - Wikipedia

    en.wikipedia.org/wiki/Lenalidomide

    Lenalidomide, sold under the brand name Revlimid among others, is a medication used to treat multiple myeloma, smoldering myeloma, and myelodysplastic syndromes (MDS). [8] For multiple myeloma, it is a first line treatment, and is given with dexamethasone . [ 8 ]

  3. Oral Anti-Cancer Therapy REVLIMID® (lenalidomide) Now ... - AOL

    www.aol.com/news/2013-06-17-oral-anti-cancer...

    Oral Anti-Cancer Therapy REVLIMID ® (lenalidomide) Now Indicated as a Treatment for Patients with Rare Form of Blood Disease Treatment indicated for patients with transfusion-dependent anaemia ...

  4. Cereblon E3 ligase modulator - Wikipedia

    en.wikipedia.org/wiki/Cereblon_E3_ligase_modulator

    The thalidomide molecule is a synthetic derivative of glutamic acid and consists of a glutarimide ring and a phthaloyl ring (Figure 5). [15] [16] Its IUPAC name is 2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione and it has one chiral center [15] After thalidomide's selective inhibition of TNF-α had been reported, a renewed effort was put in thalidomide's clinical development.

  5. Elotuzumab - Wikipedia

    en.wikipedia.org/wiki/Elotuzumab

    Among patients that had failed treatment with lenalidomide and a protease inhibitor, death or risk of progression was significantly lower in the elotuzumab study arm. [12] The median progression-free survival in the elotuzumab study arm was 10.3 months compared to 4.7 months in the control study group, after a 9.1 month follow up period.

  6. Celgene's Revlimid Faces a Tough Sell - AOL

    www.aol.com/2013/11/18/celgenes-revlimid-faces-a...

    When it comes to drug pricing, European regulators are a tough sell. Just ask Johnson & Johnson . The U.K.'s National Institute for Health and Care Excellence, or NICE, took a pass on paying for ...

  7. Celgene - Wikipedia

    en.wikipedia.org/wiki/Celgene

    Celgene Corporation is a pharmaceutical company that makes cancer and immunology drugs. Its major product is Revlimid (lenalidomide), which is used in the treatment of multiple myeloma, and also in certain anemias.

  8. Celgene's Bet on Epizyme Pays Off - AOL

    www.aol.com/news/2014-01-11-celgenes-bet-on...

    A healthy payment from big biotech Celgene Corporation helped Epizyme Inc. make one of the biggest moves in biotech so far this year. News that Epizyme Inc.'s EPZ-5676 met its proof of concept ...

  9. Pomalidomide - Wikipedia

    en.wikipedia.org/wiki/Pomalidomide

    Pomalidomide, sold under the brand names Pomalyst and Imnovid, [7] [8] is an anti-cancer medication used for the treatment of multiple myeloma and AIDS-related Kaposi sarcoma. [7] Pomalidomide was approved for medical use in the United States in February 2013, [10] and in the European Union in August 2013. [8] It is available as a generic ...