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Cyproheptadine, sold under the brand name Periactin among others, is a first-generation antihistamine with additional anticholinergic, antiserotonergic, and local anesthetic properties. It was patented in 1959 and came into medical use in 1961. [ 5 ]
Cyproheptadine, a non-selective serotonin receptor antagonist (including of the serotonin 5-HT 2A receptor), is used as an antidote in the treatment of serotonin syndrome (or serotonin toxicity) caused by serotonergic drugs, including the toxicity of serotonergic psychedelics like the NBOMe drugs.
Over-the-counter (OTC) medicines at FamilyDoctor.org, maintained by the American Academy of Family Physicians. Contains extensive information on over-the-counter drugs and their responsible use, including specific guidance on several drug classes in question-and-answer format and information on common drug interactions.
To prevent dryness, consider using an over-the-counter nasal saline spray or gel. “They are like lotion for a dry or irritated nose,” says Dr. Edwards. “Saline is helpful for most nasal ...
Aspirin is an over-the-counter medication used for a variety of reasons, but particularly in heart attack and stroke prevention for older people. Dr. Michael J. Blaha, MD, ...
To make these medicines widely available without breaking the bank, the U.S. Food and Drug Administration (FDA) should do what it already does with some insulin products: Let consumers buy them ...
Cyproheptadine; Common structural features ... Over-the-counter. H 1 receptor antagonists that are approved for over-the-counter sale in the United States, ...
The serotonin antagonist cyproheptadine is the recommended initial therapy, although there have been no controlled trials demonstrating its efficacy for SS. [ 9 ] [ 69 ] [ 70 ] Despite the absence of controlled trials, there are a number of case reports detailing apparent improvement after people have been administered cyproheptadine. [ 9 ]
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